New drug combo aims to control tough cancers in kids and adults

NCT ID NCT05210413

First seen Jan 18, 2026 · Last updated Jun 14, 2026 · Updated 23 times

Summary

This study tests a combination of two drugs (spartalizumab and low-dose pazopanib) in 80 children and adults whose solid tumors have not responded to standard treatments. The goal is to see if the combo can shrink or stabilize the cancer for at least 6 months. The pediatric part finds the safest dose, while the adult part measures how well the treatment controls the disease.

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Contacts and locations

Locations

  • APHM Hôpital des Enfants La Timone - Hématologie Oncologie Pédiatrique

    Marseille, 13385, France

  • CHU d'Angers - Unité d'Hématologie et d'Oncologie pédiatrique

    Angers, France

  • CHU de Bordeaux - Unité d'Hématologie et d'Oncologie pédiatrique

    Bordeaux, 33076, France

  • Centre Léon Bérard - Oncologie Médicale

    Lyon, 69373, France

  • Centre Oscar Lambret - Oncologie pédiatrie

    Lille, 59020, France

  • Curie Institute

    Paris, France

  • Gustave Roussy - Oncologie pédiatrique

    Villejuif, 94805, France

  • Institut Bergonié - Oncologie Médicale

    Bordeaux, 33076, France

  • Institut Curie - Centre D'Oncologie SIREDO

    Paris, 75005, France

  • Institut d'Hématologie et d'Oncologie Pédiatrique (IHOP) - Oncologie pédiatrique

    Lyon, 69373, France

  • Nantes University Hospital

    Nantes, France

  • Oscar Lambret Center

    Lille, France

  • Strasbourg University Hospital

    Strasbourg, France

Conditions

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