New drug combo aims to control tough cancers in kids and adults
NCT ID NCT05210413
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a combination of two drugs (spartalizumab and low-dose pazopanib) in 80 children and adults whose solid tumors have not responded to standard treatments. The goal is to see if the combo can shrink or stabilize the cancer for at least 6 months. The pediatric part finds the safest dose, while the adult part measures how well the treatment controls the disease.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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APHM Hôpital des Enfants La Timone - Hématologie Oncologie Pédiatrique
Marseille, 13385, France
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CHU d'Angers - Unité d'Hématologie et d'Oncologie pédiatrique
Angers, France
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CHU de Bordeaux - Unité d'Hématologie et d'Oncologie pédiatrique
Bordeaux, 33076, France
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Centre Léon Bérard - Oncologie Médicale
Lyon, 69373, France
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Centre Oscar Lambret - Oncologie pédiatrie
Lille, 59020, France
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Curie Institute
Paris, France
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Gustave Roussy - Oncologie pédiatrique
Villejuif, 94805, France
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Institut Bergonié - Oncologie Médicale
Bordeaux, 33076, France
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Institut Curie - Centre D'Oncologie SIREDO
Paris, 75005, France
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Institut d'Hématologie et d'Oncologie Pédiatrique (IHOP) - Oncologie pédiatrique
Lyon, 69373, France
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Nantes University Hospital
Nantes, France
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Oscar Lambret Center
Lille, France
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Strasbourg University Hospital
Strasbourg, France