University Hospital, Bordeaux

This study looks at two ways to drain urine from the bladder before surgery for an enlarged prostate: a tube left in place (indwelling catheter) or a tube you insert yourself several times a day (clean intermittent self-catheterization). The goal is to see which method leads to f…

This study looks at a drug called imlifidase that temporarily removes harmful antibodies from the blood, allowing highly sensitized kidney patients to receive a transplant from a donor they would otherwise reject. About 450 adults who are unlikely to get a kidney through standard…

This study looks at newborn boys with posterior urethral valves (PUV), a rare birth defect that raises the risk of serious kidney infections. It compares circumcision alone versus circumcision plus daily antibiotics to see if the surgery alone is enough to prevent these infection…

This study tests whether having general practitioners hand out colorectal cancer screening kits directly to eligible patients (ages 50-74) during visits increases screening rates compared to the usual method of mailing an invitation to make an appointment. About 26,260 people wil…

This study examines how much the tensor fascia latae muscle is damaged during hip replacement surgery through the front approach. Researchers will compare the amount of muscle damage to how well patients recover at 6 weeks and 6 months. The goal is to understand if less muscle da…

This study follows 4200 mothers and their children for 5 years to see if inducing labor at 39 weeks (instead of waiting for natural labor) affects the child's brain development. Researchers will assess thinking, language, movement, and behavior skills. The goal is to help pregnan…

This study looks back at 400 adults in France who had a rare but serious blood vessel infection caused by the bacteria Coxiella burnetii. The goal is to learn why some patients die within two years and how to diagnose the infection faster. Researchers will review medical records …

This study tests a new DNA sequencing method that reads long stretches of DNA to find hidden genetic changes causing rare diseases like albinism and intellectual disability. Researchers will analyze stored blood or DNA from 150 patients who haven't gotten a clear diagnosis yet. T…

This study looks at 60 people with acute myeloid leukemia to see if a computer program can find leftover cancer cells as accurately as trained experts. Researchers will compare results from both methods using stored blood samples. The goal is to make detection faster and more con…

This study looks back at 300 cases from 12 French hospitals over 10 years to understand rare but life-threatening fungal infections in blood vessel grafts. Researchers aim to describe what happens, how patients are treated, and what factors affect survival. The goal is to find be…

This study follows 50 adults and children who are starting long-term parenteral nutrition (nutrition given through a vein). Researchers will measure a type of sugar-related waste called AGEs in the skin over 12 months to see how much builds up. The goal is to understand health ri…

This study will collect tumor samples from 150 adults with non-small cell lung cancer (stages I to IV) to learn why the cancer grows, spreads, or returns after treatment. Researchers will analyze the genes, metabolism, and immune cells in the tumors and link these findings to pat…

This study looks at a type of immune cell called peripheral helper T-cells (Tph) in people with Common Variable Immunodeficiency (CVID) who have non-infectious complications. Researchers want to see if these cells help faulty B-cells produce antibodies that may cause harm. The st…

This study aims to develop a new way to detect if a coma patient has hidden awareness (cognitive-motor dissociation) by analyzing brain signals after a mild wrist nerve stimulation. Researchers will enroll 50 adults in intensive care with severe brain injury and a low Glasgow Com…

This study looks at whether social and psychological factors, like beliefs about back pain, are linked to spine posture in people with healthy spines. About 150 adults will fill out questionnaires and have a special X-ray to measure their spine alignment. The goal is to understan…

This study looks at whether a special nurse consultation before stroke patients go home helps them stick to their medications and care plan. About 300 adults who had a mild stroke and are returning home will take part. Half will get the extra nurse talk; the other half will get u…

This study will test a new, non-invasive ultrasound technique to measure brain blood flow in real time for infants under 2 years old with congenital heart disease. Researchers want to understand how heart defects and treatments affect the brain, which may help explain why some ch…

This study looks at whether young people (ages 8–25) with chronic immune thrombocytopenic purpura (ITP) have lower aerobic fitness than healthy peers. Fatigue is a major problem for many with ITP, and the researchers want to see if it's linked to a 'vicious cycle' of being less a…

This study looks at whether a video call (teleconsultation) works as well as an in-person visit for checking pregnant patients before they receive anesthesia during delivery. About 250 first-time mothers will take part, and researchers will compare how complete and accurate the i…

This study looks at why people with Noonan syndrome often bleed easily. Researchers will compare a simple questionnaire about bleeding with blood tests in 100 patients. The goal is to find out which tests best predict serious bleeding, especially before surgeries, to help doctors…

This study aims to create a computer model, or 'digital twin,' of a person's heart to better predict who is at risk for sudden cardiac death after a first heart attack. Researchers will enroll 1000 people who have had a heart attack and track them for two years. The goal is to se…

This study examines whether a rare genetic disorder called Alpha-1 Antitrypsin Deficiency (AATD) is more common in people who develop liver cancer (hepatocellular carcinoma) without having cirrhosis or other known risk factors. Researchers will review medical records of 71 adults…

This study aims to understand why glioblastoma, an aggressive brain cancer, returns after treatment. Researchers will analyze blood and tumor samples from 45 adults having surgery for newly diagnosed or recurrent glioblastoma. The goal is to identify new targets for better therap…

This study looks at stored liver biopsy samples from 30 people with MASH (a fatty liver disease) to see if a protein test can predict who will develop liver cancer within 15 years. Half of the participants later got liver cancer, and half did not. Researchers will compare the pro…