Could circumcision replace antibiotics for preventing kidney infections in newborns with PUV?

NCT ID NCT07527442

First seen May 13, 2026 · Last updated Jun 16, 2026 · Updated 6 times

Summary

This study looks at newborn boys with posterior urethral valves (PUV), a rare birth defect that raises the risk of serious kidney infections. It compares circumcision alone versus circumcision plus daily antibiotics to see if the surgery alone is enough to prevent these infections. About 72 boys will be followed for two years to track infection rates and kidney health.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • APHM

    Marseille, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • APHP Hôpital Armand Trousseau

    Paris, 75012, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • APHP Hôpital Necker

    Paris, 75015, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • APHP Hôpital Robert Debré

    Paris, 75019, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU de Besançon

    Besançon, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU de Bordeaux

    Bordeaux, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU de Limoges

    Limoges, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU de Montpellier

    Montpellier, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU de Nantes

    Nantes, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU de Reims

    Reims, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU de Rennes

    Rennes, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU de Toulouse

    Toulouse, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU de la Réunion

    Saint-Denis, 97400, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.