Eli Lilly And Company

This early-stage study tested a new drug called eloralintide, given alone or together with tirzepatide, in 188 adults with overweight or obesity. The main goals were to check safety, side effects, and how the drugs move through the body. Participants received weekly injections un…

This study tested a drug called mirikizumab in people with moderate to severe ulcerative colitis who had already responded to initial treatment. The goal was to see if the drug could keep the disease under control over 40 weeks. About 1,177 adults took part, and the main measure …

This study tested a connected insulin management platform to see if it helps people with type 1 or type 2 diabetes take their insulin doses on time and keep their blood sugar in a healthy range. About 36 participants used the platform along with continuous glucose monitoring. The…

This study tested the safety and effectiveness of adding the drug abemaciclib to standard chemotherapy for children and young adults (up to age 18) whose solid tumors, including neuroblastoma, had stopped responding to treatment or had grown. The goal was to find the best dose an…

This study tested a drug called donanemab (LY3002813) in 272 people with early-stage Alzheimer's disease. The goal was to see if it is safe and can slow down memory and thinking problems. Participants received either the drug or a placebo, and their cognitive abilities were measu…

This study tested two weight-loss medications, tirzepatide and semaglutide, in 751 adults with obesity or overweight who also had related health problems like high blood pressure. Participants did not have diabetes. The trial lasted about 74 weeks and measured how much weight peo…

This study tested an oral drug called LOXO-305 in 87 Chinese adults with chronic lymphocytic leukemia, small lymphocytic lymphoma, or non-Hodgkin lymphoma whose cancer had returned or not responded to prior treatments. The main goal was to see how many patients had their tumors s…

This study looked at how a single dose of the experimental drug LY3209590 enters and leaves the blood in children with type 2 diabetes. Fifteen children took part, and the study lasted about 100 days. The goal was to understand the drug's processing in the body, not to treat the …

This study tested a new once-daily pill, orforglipron, against an existing pill (oral semaglutide) in 1698 adults with type 2 diabetes whose blood sugar was not well controlled by metformin alone. The goal was to see which pill works better at lowering blood sugar and body weight…

This study tested the drug tirzepatide in children and teenagers aged 10 to 17 with type 2 diabetes that was not well controlled by metformin or insulin. The goal was to see if tirzepatide could lower blood sugar levels better than a placebo. Participants took the drug or a place…

This study tested a once-daily oral medication called orforglipron to see if it helps adults with obesity or overweight and type 2 diabetes lose weight. About 1,600 participants took either the drug or a placebo for 77 weeks. The main goal was to measure changes in body weight, a…

This study tested a once-weekly medicine called retatrutide in 445 people who are overweight or have obesity and also have knee osteoarthritis. The goal was to see if it helps with weight loss and reduces knee pain. The study lasted about 77 weeks and compared the drug to a place…

This study looked at how a single dose of the cancer drug Selpercatinib (LOXO-292) affects the heart's electrical activity in 32 healthy adults. Participants took the drug, a placebo, or a positive control in random order, and had their heart rhythm measured by ECG. The goal was …

This early-stage study tested a new drug called LY4060874 in 121 healthy adults to see if it is safe and how the body processes it. Participants were monitored for side effects over up to 22 weeks. The study did not aim to treat any disease, only to gather safety information.

This study tested a new drug called LY4268989 in 144 healthy adults, including Japanese and Chinese participants. The goal was to see how the body absorbs and processes the drug, how safe it is, and whether food or other medications affect it. No treatment benefit was expected; t…

This study looked at how food and certain drugs (omeprazole, itraconazole, carbamazepine) affect the levels of a new medicine called LY3484356 in the blood. It involved 82 healthy women who cannot become pregnant. The goal was to understand how the body processes the drug, not to…

This early-stage study looked at how a single dose of the drug LY3526318 affects blood flow in the skin of healthy women. Researchers used special imaging to measure changes after applying a cinnamon-like substance. The study involved 16 participants and was completed by Eli Lill…

This early-stage study tested a new drug called LY3985863 in 24 healthy Chinese adults to see if it is safe and what side effects it might cause. Participants received multiple doses under the skin or a placebo, and blood tests measured how the drug moves through the body. Since …

This early-stage study tested a new drug called LY3451838 in 53 healthy adults to see if it is safe and how the body handles it. Participants received a single dose either into a vein or just under the skin. The main goal was to check for side effects and measure how the drug mov…