Could this drug clear Alzheimer's brain plaques? major trial results are in

NCT ID NCT05463731

First seen May 27, 2026 · Last updated Jun 13, 2026 · Updated 5 times

Summary

This study tested an experimental drug called remternetug in 1667 people with early symptoms of Alzheimer's disease. The main goal was to see if the drug could safely clear amyloid plaques from the brain, a hallmark of Alzheimer's. Participants received either the drug or a placebo, and researchers measured plaque reduction using brain scans.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • AMC Research

    Matthews, North Carolina, 28105, United States

  • AMITA Health - Alexian Brothers Neurosciences Institute Clinical Research

    Elk Grove Village, Illinois, 60007, United States

  • Adams Clinical

    Watertown, Massachusetts, 02472, United States

  • Advanced Memory Research Institute of New Jersey

    Toms River, New Jersey, 08755, United States

  • Alpine Clinical Research Center

    Boulder, Colorado, 80301, United States

  • Alzheimer's Research and Treatment Center

    Stuart, Florida, 34997, United States

  • Alzheimer's Research and Treatment Center

    Wellington, Florida, 33414, United States

  • Anderson Clinical Research

    Redlands, California, 92374, United States

  • Brain Matters Research

    Delray Beach, Florida, 33445, United States

  • Brain Matters Research

    Stuart, Florida, 34997, United States

  • Care Access - Lake Charles

    Lake Charles, Louisiana, 70601, United States

  • Carteret Medical Group

    Morehead City, North Carolina, 28557, United States

  • Center for Cognitive Health

    Portland, Oregon, 97225, United States

  • Central Texas Neurology Consultants

    Round Rock, Texas, 78681, United States

  • Charter Research - Lady Lake

    The Villages, Florida, 32162, United States

  • Charter Research - Winter Park

    Orlando, Florida, 32803, United States

  • Citizens Memorial Hospital District

    Bolivar, Missouri, 65613, United States

  • ClinCloud - Maitland

    Maitland, Florida, 32751, United States

  • ClinCloud - Viera

    Melbourne, Florida, 32940, United States

  • Clinical Research Professionals

    Chesterfield, Missouri, 63005, United States

  • Colorado Springs Neurological Associates

    Colorado Springs, Colorado, 80907, United States

  • Columbus Memory Center, PC

    Columbus, Georgia, 31909, United States

  • Conquest Research

    Winter Park, Florida, 32789, United States

  • Consano Clinical Research, LLC

    Shavano Park, Texas, 78231, United States

  • Cotton O'Neil Clinical Research Center - Central Office

    Topeka, Kansas, 66606, United States

  • Covenant Medical Center

    Waterloo, Iowa, 50702, United States

  • Emerald Coast Neurology - Airport Boulevard

    Pensacola, Florida, 32504, United States

  • Encore Research Group- Jacksonville Center for Clinical Research

    Jacksonville, Florida, 32216, United States

  • Finlay Medical Research

    Greenacres City, Florida, 33467, United States

  • Gadolin Research

    Beaumont, Texas, 77702, United States

  • Great Lakes Clinical Trials - Andersonville

    Chicago, Illinois, 60640, United States

  • Hope Clinical Research, Inc.

    Canoga Park, California, 91303, United States

  • Institute for Neurodegenerative Disorders

    New Haven, Connecticut, 06510, United States

  • Irvine Clinical Research

    Irvine, California, 92614, United States

  • JEM Research Institute

    Atlantis, Florida, 33462, United States

  • K2 Medical Research

    Maitland, Florida, 32751, United States

  • Kaizen Brain Center

    La Jolla, California, 92037, United States

  • Katayama Medical Clinic

    Kurashiki, Okayama-ken, 710-0813, Japan

  • Kerwin Medical Center

    Dallas, Texas, 75231, United States

  • Keystone Clinical Studies

    Plymouth Meeting, Pennsylvania, 19462, United States

  • Ki Health Partners, LLc, dba New England Institute for Clinical Research

    Stamford, Connecticut, 06905, United States

  • Las Vegas Medical Research

    Las Vegas, Nevada, 89128, United States

  • MD First Research - Chandler

    Chandler, Arizona, 85286, United States

  • MedVadis Research Corporation

    Waltham, Massachusetts, 02451, United States

  • Memory Clinic Ochanomizu

    Bunkyo-ku, Tokyo, 113-0034, Japan

  • Memory Clinic Toride

    Toride, Ibaraki, 302-0004, Japan

  • Merritt Island Medical Research, LLC

    Merritt Island, Florida, 32952, United States

  • Mountain Neurological Research Center

    Basalt, Colorado, 81621, United States

  • National Clinical Research, Inc

    Richmond, Virginia, 23294, United States

  • Neuro-Pain Medical Center

    Fresno, California, 93710, United States

  • NeuroScience Research Center

    Canton, Ohio, 44718, United States

  • Neurological Associates Albany

    Albany, New York, 12208, United States

  • Neurology Clinic, P.C.

    Cordova, Tennessee, 38018, United States

  • Neurology Consultants of Dallas, PA

    Dallas, Texas, 75243, United States

  • Neurology Diagnostics, Inc.

    Dayton, Ohio, 45459, United States

  • Neuropsychiatric Research Center of Southwest Florida

    Fort Myers, Florida, 33912, United States

  • North County Neurology Associates

    Carlsbad, California, 92011, United States

  • Northwest Clinical Research Center

    Bellevue, Washington, 98007, United States

  • Optimus U Corporation

    Miami, Florida, 33135, United States

  • Palm Beach Neurology

    West Palm Beach, Florida, 33407, United States

  • Progressive Medical Research

    Port Orange, Florida, 32127, United States

  • Re:Cognition Health

    Fairfax, Virginia, 22031, United States

  • Renstar Medical Research

    Ocala, Florida, 34470, United States

  • Rhode Island Mood & Memory Research Institute

    East Providence, Rhode Island, 02914, United States

  • Suncoast Clinical Research, Inc.

    New Port Richey, Florida, 34652, United States

  • Tallahassee Neurological Clinic

    Tallahassee, Florida, 32308, United States

  • Texas Diabetes & Endocrinology, P.A.

    Austin, Texas, 78749, United States

  • The Clinical Trial Center, LLC

    Jenkintown, Pennsylvania, 19046, United States

  • The Cognitive and Research Center of New Jersey

    Springfield, New Jersey, 07081, United States

  • The University of Texas Health Science Center at Houston

    Houston, Texas, 77054, United States

  • Universal Research Group

    Tacoma, Washington, 98405, United States

  • VIN-Andrew Lerman

    Miami, Florida, 33133, United States

  • VIN-Julie Schwartzbard

    Aventura, Florida, 33180, United States

  • Valley Medical Research

    Centerville, Ohio, 45459, United States

  • Wr- Pri, Llc

    Encino, California, 91316, United States

  • iResearch Atlanta

    Decatur, Georgia, 30030, United States

Conditions

Explore the condition pages connected to this study.