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New hope for kids with rare abdominal cancer: drug combo tested

NCT ID NCT04145349

Completed Disease control Sponsor: Eli Lilly and Company Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 07, 2026 · Updated 1 time

Summary

This study tested a drug called ramucirumab, given with standard chemotherapy, for children and young adults with a rare cancer called desmoplastic small round cell tumor (DSRCT) that had come back or not responded to treatment. The goal was to see if the combination could slow tumor growth. The trial enrolled 30 participants and lasted up to a year or more, depending on how well the tumor responded.

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Conditions

The condition(s) this trial relates to.

desmoplastic small round cell tumor sarcoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DESMOPLASTIC SMALL ROUND CELL TUMOR

Contacts and locations

Locations

  • Azienda Ospedaliera di Padova

    Padova, Veneto, 35128, Italy

  • Children's Hospital of Los Angeles

    Los Angeles, California, 90027, United States

  • Children's Hospital of Philadelphia (CHOP)

    Philadelphia, Pennsylvania, 19104, United States

  • Children's National Medical Center

    Washington D.C., District of Columbia, 20010, United States

  • Fondazione IRCCS Istituto Nazionale dei Tumori

    Milan, Lombardy, 20133, Italy

  • Hospital Universitari Vall d'Hebron

    Barcelona, Barcelona [Barcelona], 08035, Spain

  • Hospital Universitario Virgen Del Rocio

    Seville, 41013, Spain

  • Humanitas

    Rozzano, Milano, 20089, Italy

  • Kyushu University Hospital

    Fukuoka, 812-8582, Japan

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • National Cancer Center Hospital

    Chuo-ku, Tokyo, 104-0045, Japan

  • Ospedale Pediatrico Bambino Gesù

    Rome, Roma, 165, Italy

  • Phoenix Children's Hospital

    Phoenix, Arizona, 85016, United States

  • Royal Children's Hospital

    Parkville, Victoria, 3052, Australia

  • Royal Manchester Children's Hospital

    Manchester, M13 9WL, United Kingdom

  • Royal Marsden Hospital (Sutton)

    London, Sutton, SM2 5PT, United Kingdom

  • The Christie

    Manchester, M20 4BX, United Kingdom

  • Universitaetsklinikum Essen

    Essen, North Rhine-Westphalia, 45122, Germany

  • Universitaetsklinikum Freiburg

    Freiburg im Breisgau, Baden-Wurttemberg, 79106, Germany

  • Universitaetsklinikum Hamburg-Eppendorf

    Hamburg, 20251, Germany

  • University College London Hospital

    London, London, City of, NW1 2PG, United Kingdom

  • Washington University

    St Louis, Missouri, 63110, United States

More trials for these conditions

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