New hope for kids with rare tumor: drug combo trial launches
NCT ID NCT04145349
First seen Jan 04, 2026 · Last updated Apr 28, 2026 · Updated 16 times
Summary
This study tests whether adding the drug ramucirumab to standard chemotherapy can help children and young adults with a rare cancer called desmoplastic small round cell tumor (DSRCT) that has returned or not responded to prior treatment. About 30 participants will receive either ramucirumab plus chemo or chemo alone. The goal is to see if the combination slows tumor growth and is safe. Participation may last a year or longer.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Azienda Ospedaliera di Padova
Padova, Veneto, 35128, Italy
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Children's Hospital of Los Angeles
Los Angeles, California, 90027, United States
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Children's Hospital of Philadelphia (CHOP)
Philadelphia, Pennsylvania, 19104, United States
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Children's National Medical Center
Washington D.C., District of Columbia, 20010, United States
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Fondazione IRCCS Istituto Nazionale dei Tumori
Milan, Lombardy, 20133, Italy
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Hospital Universitari Vall d'Hebron
Barcelona, Barcelona [Barcelona], 08035, Spain
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Hospital Universitario Virgen Del Rocio
Seville, 41013, Spain
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Humanitas
Rozzano, Milano, 20089, Italy
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Kyushu University Hospital
Fukuoka, 812-8582, Japan
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
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National Cancer Center Hospital
Chuo-ku, Tokyo, 104-0045, Japan
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Ospedale Pediatrico Bambino Gesù
Rome, Roma, 165, Italy
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Phoenix Children's Hospital
Phoenix, Arizona, 85016, United States
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Royal Children's Hospital
Parkville, Victoria, 3052, Australia
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Royal Manchester Children's Hospital
Manchester, M13 9WL, United Kingdom
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Royal Marsden Hospital (Sutton)
London, Sutton, SM2 5PT, United Kingdom
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The Christie
Manchester, M20 4BX, United Kingdom
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Universitaetsklinikum Essen
Essen, North Rhine-Westphalia, 45122, Germany
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Universitaetsklinikum Freiburg
Freiburg im Breisgau, Baden-Wurttemberg, 79106, Germany
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Universitaetsklinikum Hamburg-Eppendorf
Hamburg, 20251, Germany
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University College London Hospital
London, London, City of, NW1 2PG, United Kingdom
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Washington University
St Louis, Missouri, 63110, United States
Conditions
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