DESMOPLASTIC SMALL ROUND CELL TUMOR
Clinical trials for DESMOPLASTIC SMALL ROUND CELL TUMOR explained in plain language.
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New stem cell approach aims to fight tough childhood cancers
Disease control Recruiting nowThis study tests a special stem cell transplant for children, teens, and young adults (ages 6 months to 25 years) with solid tumors that have come back or not responded to treatment. The transplant uses cells from a donor, with certain immune cells removed to reduce side effects,…
Matched conditions: DESMOPLASTIC SMALL ROUND CELL TUMOR
Phase: PHASE1, PHASE2 • Sponsor: University of Florida • Aim: Disease control
Last updated Jul 02, 2026 00:00 UTC
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New drug cocktail targets rare childhood cancer
Disease control Recruiting nowThis study tests a combination of two chemotherapy drugs, lurbinectedin and irinotecan, in 20 patients aged 15 and older with advanced desmoplastic small round cell tumor (DSRCT) that cannot be surgically removed. The goal is to shrink or control the tumor and track side effects.…
Matched conditions: DESMOPLASTIC SMALL ROUND CELL TUMOR
Phase: PHASE2 • Sponsor: Italian Sarcoma Group • Aim: Disease control
Last updated Jun 27, 2026 13:06 UTC
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New hope for kids with tough cancers: drug combo trial launches
Disease control Recruiting nowThis study tests a new cancer drug, repotrectinib, combined with standard chemotherapy in children and young adults with advanced solid tumors that have spread. The goal is to find the safest dose and see if the combination can shrink tumors. Researchers will also study how the b…
Matched conditions: DESMOPLASTIC SMALL ROUND CELL TUMOR
Phase: PHASE1, PHASE2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 13:04 UTC
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New cocktail of four drugs aims to tackle childhood cancers that Won't go away
Disease control Recruiting nowThis study is testing a combination of four drugs—atezolizumab, sorafenib, bevacizumab, and cyclophosphamide—in children and young adults with solid tumors that have come back or not responded to standard treatment. The goal is to find safe doses and see if the combination can sh…
Matched conditions: DESMOPLASTIC SMALL ROUND CELL TUMOR
Phase: PHASE1, PHASE2 • Sponsor: St. Jude Children's Research Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:36 UTC
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Engineered immune cells take aim at childhood cancers
Disease control Recruiting nowThis early-stage trial tests a new immunotherapy for children and young adults up to age 21 with solid tumors that have come back or not responded to standard treatment. The therapy uses the patient's own immune cells, which are modified in a lab to recognize and attack a protein…
Matched conditions: DESMOPLASTIC SMALL ROUND CELL TUMOR
Phase: PHASE1 • Sponsor: St. Jude Children's Research Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:35 UTC
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Promising drug targets rare childhood cancers in new trial
Disease control Recruiting nowThis study tests a drug called lurbinectedin in people aged 10 and older whose solid tumors (like Ewing sarcoma) have returned after standard treatment. The goal is to see if the drug is safe and can shrink tumors or delay their growth. Participants must have a specific genetic c…
Matched conditions: DESMOPLASTIC SMALL ROUND CELL TUMOR
Phase: PHASE1, PHASE2 • Sponsor: Children's Hospital of Philadelphia • Aim: Disease control
Last updated Jun 27, 2026 12:01 UTC
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New hope for tough tumors: Half-Matched bone marrow transplant trial
Disease control Recruiting nowThis study is testing a bone marrow transplant from a half-matched family donor for people with high-risk solid tumors that have come back or not responded to treatment. Participants receive mild chemotherapy and radiation before the transplant, along with drugs to prevent reject…
Matched conditions: DESMOPLASTIC SMALL ROUND CELL TUMOR
Phase: PHASE2 • Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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New drug cocktail aims to keep childhood cancers at bay
Disease control Recruiting nowThis phase 2 trial tests whether a year-long maintenance regimen of sirolimus (rapamycin) plus low-dose oral chemotherapy and celecoxib can improve 2-year survival without cancer progression in children with high-risk solid tumors. About 55 children and young adults (ages 1–30) w…
Matched conditions: DESMOPLASTIC SMALL ROUND CELL TUMOR
Phase: PHASE2 • Sponsor: Emory University • Aim: Disease control
Last updated Jun 27, 2026 09:09 UTC
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New drug cocktail aims to tackle tough sarcomas in young patients
Disease control Recruiting nowThis study tests a new drug called PEEL-224 combined with two standard chemotherapy drugs (vincristine and temozolomide) in adolescents and young adults whose sarcomas have returned or not responded to treatment. The trial has two phases: first, finding the safest dose, then chec…
Matched conditions: DESMOPLASTIC SMALL ROUND CELL TUMOR
Phase: PHASE1, PHASE2 • Sponsor: David S Shulman, MD • Aim: Disease control
Last updated Jun 27, 2026 09:05 UTC
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New hope for sarcoma patients: immunotherapy plus chemo shows promise
Disease control Recruiting nowThis study tests a new combination of drugs (tislelizumab, liposomal doxorubicin, and ifosfamide) as a first treatment for people with advanced soft tissue sarcoma that cannot be removed by surgery or has spread. The goal is to see if this combo shrinks tumors and is safe. About …
Matched conditions: DESMOPLASTIC SMALL ROUND CELL TUMOR
Phase: PHASE2 • Sponsor: Fudan University • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC
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Scientists launch deep dive into rare sarcomas to unlock immune secrets
Knowledge-focused Recruiting nowThis study is collecting tumor and blood samples from 400 people with rare soft tissue sarcomas to learn how their immune system reacts to the cancer. Researchers will also track patients' health over time to see how the disease progresses. The goal is to find clues that could le…
Matched conditions: DESMOPLASTIC SMALL ROUND CELL TUMOR
Phase: NA • Sponsor: Institut Claudius Regaud • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC
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New DSRCT registry aims to unlock secrets of rare cancer
Knowledge-focused Recruiting nowThis study is a patient registry for people diagnosed with desmoplastic small round cell tumor (DSRCT), a rare cancer. Researchers will collect health information from up to 250 participants of any age to build a database for current and future studies. The goal is to better unde…
Matched conditions: DESMOPLASTIC SMALL ROUND CELL TUMOR
Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC