New drug cocktail targets rare childhood cancer

NCT ID NCT07328425

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a combination of two chemotherapy drugs, lurbinectedin and irinotecan, in 20 patients aged 15 and older with advanced desmoplastic small round cell tumor (DSRCT) that cannot be surgically removed. The goal is to shrink or control the tumor and track side effects. An optional part of the study looks at tumor genes to understand how the cancer behaves and responds to treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

desmoplastic small round cell tumor

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Fondazione IRCCS Istituto Nazionale dei Tumori

    RECRUITING

    Milan, 20133, Italy

    Contact Email: •••••@•••••

    Contact

  • Fondazione Policlinico Universitario Campus Bio-Medico

    RECRUITING

    Roma, 00128, Italy

    Contact

    Contact

  • Fondazione del Piemonte per l'Oncologia IRCCS

    RECRUITING

    Candiolo, Torino, 10060, Italy

    Contact

    Contact Email: •••••@•••••

  • IOV Istituto Oncologico Veneto IRCCS

    RECRUITING

    Padova, 35128, Italy

    Contact

    Contact Email: •••••@•••••

  • Nuovo Ospedale "S.Stefano"

    RECRUITING

    Prato, 59100, Italy

    Contact

    Contact Email: •••••@•••••