New hope for tough tumors: Half-Matched bone marrow transplant trial

NCT ID NCT01804634

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing a bone marrow transplant from a half-matched family donor for people with high-risk solid tumors that have come back or not responded to treatment. Participants receive mild chemotherapy and radiation before the transplant, along with drugs to prevent rejection. The goal is to see if this approach is safe and can help control the disease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

bone marrow transplant from a half-matched related donor

What this could lead to

If successful, this could offer a new treatment option for patients with hard-to-treat solid tumors that have not responded to standard therapies.

What could go wrong

This is an early phase II trial with only 60 participants, so results may not apply to everyone. The procedure carries serious risks, including graft-versus-host disease and infection.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for DESMOPLASTIC SMALL ROUND CELL TUMOR are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

desmoplastic small round cell tumor Ewing sarcoma ganglioneuroblastoma hepatoblastoma metastatic malignant neoplasm neuroblastoma osteosarcoma rhabdomyosarcoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Albert Einstein College of Medicine, Children's Hospital at Montefiore

    RECRUITING

    The Bronx, New York, 10467, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • New York Medical Center/ Maria Fareri Children's Hospital

    RECRUITING

    Valhalla, New York, 10595, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

  • The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

    RECRUITING

    Baltimore, Maryland, 21231, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact