New hope for eczema patients when first treatment fails

NCT ID NCT05369403

Completed Disease control Sponsor: Eli Lilly and Company Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a drug called lebrikizumab in 86 adults and teens with moderate-to-severe eczema who had already tried dupilumab. The goal was to see if lebrikizumab could safely improve their skin condition. Researchers measured how many participants achieved at least a 75% improvement in eczema severity after 16 and 24 weeks of treatment.

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Conditions

The condition(s) this trial relates to.

atopic eczema Eczema

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATOPIC DERMATITIS

Contacts and locations

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Locations

Advanced Medical Research

Sandy Springs, Georgia, 30328, United States
Allcutis Research, Inc

Portsmouth, New Hampshire, 03801, United States
Allcutis Research, Inc.

Beverly, Massachusetts, 01915, United States
Avance Clinical Trials Inc

Laguna Niguel, California, 92677, United States
Axon Clinical Research

Inglewood, California, 90301, United States
Clinical Partners, LLC

Johnston, Rhode Island, 02919, United States
Clinical Science Institute

Santa Monica, California, 90404, United States
Complete Dermatology

Sugar Land, Texas, 77479, United States
Cura Clinical Research

Sherman Oaks, California, 91403, United States
Dawes Fretzin Clinical Research Group, LLC

Indianapolis, Indiana, 46250, United States
Dermatologists of Greater Columbus

Bexley, Ohio, 43209, United States
Dermatology Research Associates

Los Angeles, California, 90045, United States
Dermatology and Advanced Aesthetics

Lake Charles, Louisiana, 70605, United States
Dermatology and Skin Cancer Specialists, LLC

Rockville, Maryland, 20850, United States
Dermatology and Skin Surgery Center, PC

Exton, Pennsylvania, 19341, United States
Direct Helpers Research Center

Hialeah, Florida, 33012, United States
Dundee Dermatology

West Dundee, Illinois, 60118, United States
Encore Medical Research of Boynton Beach

Boynton Beach, Florida, 33436, United States
First OC Dermatology

Fountain Valley, California, 92708, United States
Hollywood Dermatology

Hollywood, Florida, 33021, United States
MediSearch Clinical Trials

Saint Joseph, Missouri, 64506, United States
Medical Dermatology Specialists

Phoenix, Arizona, 85006, United States
Miami Dermatology and Laser Research

Miami, Florida, 33173, United States
Oakland Hills Dermatology

Auburn Hills, Michigan, 48326, United States
Olympian Clinical Research

Tampa, Florida, 33615, United States
OptiSkin Medical

New York, New York, 10128, United States
Revival Research Institute - Troy

Troy, Michigan, 48084, United States
River Region Dermatology and Laser

Montgomery, Alabama, 36117, United States
Sadick Research Group

New York, New York, 10075, United States
Skin Care Physicians of Georgia

Macon, Georgia, 31217, United States
Spokane Dermatology Clinic

Spokane, Washington, 99202, United States
The Derm Institute of West Michigan

Caledonia, Michigan, 49316, United States
Total Vein and Skin LLC

Boynton Beach, Florida, 33437, United States
UConn Health

Farmington, Connecticut, 06030-2840, United States
Wallace Medical Group, Inc.

Los Angeles, California, 90056, United States
Windsor Dermatology, P.C.

East Windsor, New Jersey, 08520, United States
Ziaderm Research, LLC.

North Miami Beach, Florida, 33162, United States

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