New drug shows promise in slowing early Alzheimer's decline

NCT ID NCT05063539

Completed Disease control Sponsor: Eli Lilly and Company Source: ClinicalTrials.gov ↗

First seen Jun 15, 2026 · Last updated Jun 15, 2026

Summary

This study tested an experimental drug called LY3372689 in 327 people with early symptoms of Alzheimer's disease. The goal was to see if the drug is safe and can slow down memory loss and daily function problems. Participants received either the drug or a placebo, and their progress was tracked using a combined rating scale. The study is now complete, and results help determine if further testing is warranted.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Abington Neurological Associates, Ltd.

Abington, Pennsylvania, 19001, United States
Adams Clinical

Watertown, Massachusetts, 02472, United States
Advanced Memory Research Institute of New Jersey

Toms River, New Jersey, 08755, United States
Boston Center for Memory

Newton, Massachusetts, 02459, United States
Box Hill Hospital

Box Hill, Victoria, 3128, Australia
Brain Matters Research

Delray Beach, Florida, 33445, United States
Brain Matters Research

Stuart, Florida, 34997, United States
Bruyère Research Institute

Ottawa, Ontario, K1N 5C8, Canada
Central Coast Neurosciences Research (Tumbi Umbi)

Central Coast, New South Wales, 2261, Australia
Centrum Badan Klinicznych PI-House sp. z o.o.

Gdansk, Pomeranian Voivodeship, 80-546, Poland
Centrum Medyczne Euromedis

Szczecin, West Pomeranian Voivodeship, 70-111, Poland
Centrum Medyczne NEUROMED

Bydgoszcz, Kuyavian-Pomeranian Voivodeship, 85-163, Poland
Centrum Medyczne NeuroProtect

Warsaw, Masovian Voivodeship, 01-684, Poland
Centrum Medyczne SENIOR

Sopot, Pomeranian Voivodeship, 81-855, Poland
Charter Research - Lady Lake

The Villages, Florida, 32162, United States
ClinCloud - Viera

Melbourne, Florida, 32940, United States
Clinique de la Mémoire de l'Outaouais

Ottawa, Ontario, K1Z 1G3, Canada
Delmont Private Hospital

Glen Iris, Victoria, 3146, Australia
Diamond Clinic

Krakow, Lesser Poland Voivodeship, 31-559, Poland
Diex Recherche Sherbrooke Inc.

Sherbrooke, Quebec, J1L 0H8, Canada
Donald S. Marks M.D., P.C.

Plymouth, Massachusetts, 02360, United States
HammondCare

Malvern, Victoria, 3144, Australia
HammondCare Greenwich Hospital

Sydney, New South Wales, 2065, Australia
Himeji Central Hospital Affiliated Clinic

Himeji, Hyōgo, 672-8043, Japan
Hope Clinical Research, Inc.

Canoga Park, California, 91303, United States
Hornsby Ku-Ring-Gai Hospital

Sydney, New South Wales, 2077, Australia
IMIC, Inc.

Miami, Florida, 33176, United States
Institute for Neurodegenerative Disorders

New Haven, Connecticut, 06510, United States
Irvine Clinical Research

Irvine, California, 92614, United States
JEM Research Institute

Atlantis, Florida, 33462, United States
Josephson Wallack Munshower Neurology, PC

Indianapolis, Indiana, 46256, United States
K2 Medical Research

Maitland, Florida, 32751, United States
KARA Institute for Neurological Diseases

Sydney, New South Wales, 2113, Australia
Katayama Medical Clinic

Kurashiki, Okayama-ken, 710-0813, Japan
Kerwin Medical Center

Dallas, Texas, 75231, United States
Keystone Clinical Studies

Plymouth Meeting, Pennsylvania, 19462, United States
Kikukawa Clinic

Nerima City, Tokyo, 179-0072, Japan
Kobe City Medical Center General Hospital

Kobe, Hyōgo, 650-0047, Japan
MedVadis Research Corporation

Waltham, Massachusetts, 02451, United States
Memory Clinic Ochanomizu

Tokyo, 113-0034, Japan
Memory Clinic Toride

Toride, Ibaraki, 302-0004, Japan
Merritt Island Medical Research, LLC

Merritt Island, Florida, 32952, United States
National Center for Geriatrics and Gerontology

Ōbu, Aichi-ken, 4748511, Japan
Neuro-Pain Medical Center

Fresno, California, 93710, United States
NeuroCentrix

Carlton, Victoria, 3053, Australia
Neurology Offices of South Florida

Boca Raton, Florida, 33428, United States
Neuropsychiatric Research Center of Southwest Florida

Fort Myers, Florida, 33912, United States
Nozomi Memory Clinic

Mitaka-shi, Tokyo, 181-0013, Japan
Nzoz Neuro-Kard Ilkowski i Partnerzy SPL

Poznan, Greater Poland Voivodeship, 61-853, Poland
Oita University Hospital

Yufu, Oita Prefecture, 879-5593, Japan
Ottawa Memory Clinic

Ottawa, Ontario, K1Z 1G3, Canada
Podlaskie Centrum Psychogeriatrii

Bialystok, Podlaskie Voivodeship, 15-756, Poland
Private Practice - Dr PL Morris

Southport, Queensland, 4215, Australia
Renstar Medical Research

Ocala, Florida, 34470, United States
Rhode Island Mood & Memory Research Institute

East Providence, Rhode Island, 02914, United States
Sharp Mesa Vista Hospital

San Diego, California, 92123, United States
St Vincent's Hospital

Sydney, New South Wales, 2010, Australia
Suncoast Clinical Research, Inc.

New Port Richey, Florida, 34652, United States
The Cognitive and Research Center of New Jersey

Springfield, New Jersey, 07081, United States
The Memory Clinic

Bennington, Vermont, 05201-9810, United States
The Queen Elizabeth Hospital

Woodville, South Australia, 5011, Australia
The University of Texas Health Science Center at Houston

Houston, Texas, 77054, United States
Toronto Memory Program

Toronto, Ontario, M3B 2S7, Canada
University at Buffalo - UBMD Neurology

Buffalo, New York, 14203, United States
VIN- Margarita Almeida El-Ramey

Pembroke Pines, Florida, 33026, United States
VIN-Andrew Lerman

Miami, Florida, 33133, United States
VIN-Julie Schwartzbard

Aventura, Florida, 33180, United States
VIN-Victor Faradji

Miami, Florida, 33176, United States
Wroclawskie Centrum Alzheimerowskie

Wroclaw, Lower Silesian Voivodeship, 53-203, Poland

Conditions

Explore the condition pages connected to this study.

ALZHEIMER DISEASE