New eczema drug shows promise for people with darker skin

NCT ID NCT05372419

Completed Disease control Sponsor: Eli Lilly and Company Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested the drug lebrikizumab in 90 adults and teens with moderate-to-severe eczema who have skin of color. The goal was to see if the drug is safe and helps clear skin. Participants received injections over 24 weeks, and doctors measured improvement using a standard eczema severity score.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Lebrikizumab (a drug given as an injection under the skin)
What this could lead to: If successful, this could provide a treatment option specifically tested for people with skin of color who have moderate-to-severe eczema.
What could go wrong: This is a single-arm, open-label study with only 90 participants, so results may not apply to everyone. Lebrikizumab may cause side effects and is not a cure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

atopic eczema Eczema

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATOPIC DERMATITIS

Contacts and locations

Locations

Advanced Medical Research

Sandy Springs, Georgia, 30328, United States
Allcutis Research, Inc.

Beverly, Massachusetts, 01915, United States
Arlington Research Center, Inc

Arlington, Texas, 76011, United States
Avance Clinical Trials Inc

Laguna Niguel, California, 92677, United States
Axon Clinical Research

Inglewood, California, 90301, United States
Center For Dermatology Clinical Research, Inc.

Fremont, California, 94538, United States
Clinical Science Institute

Santa Monica, California, 90404, United States
Clinical Trial Network

Houston, Texas, 77074, United States
Complete Dermatology

Sugar Land, Texas, 77479, United States
Cura Clinical Research

Palmdale, California, 93551, United States
Cura Clinical Research

Sherman Oaks, California, 91403, United States
Dawes Fretzin Clinical Research Group, LLC

Indianapolis, Indiana, 46250, United States
Dermatology & Laser Center of Charleston

Charleston, South Carolina, 29407, United States
Dermatology Clinical Research Center of San Antonio

San Antonio, Texas, 78229, United States
Dermatology Research Associates

Los Angeles, California, 90045, United States
Encore Medical Research of Boynton Beach

Boynton Beach, Florida, 33436, United States
First OC Dermatology

Fountain Valley, California, 92708, United States
Miami Dermatology and Laser Research

Miami, Florida, 33173, United States
Oakland Hills Dermatology

Auburn Hills, Michigan, 48326, United States
Progressive Clinical Research

San Antonio, Texas, 78213, United States
PureSkin Dermatology

Orlando, Florida, 32819, United States
Revival Research Institute - Troy

Troy, Michigan, 48084, United States
Sadick Research Group

New York, New York, 10075, United States
Savin Medical Group, LLC

Miami Lakes, Florida, 33014, United States
Skin Care Physicians of Georgia

Macon, Georgia, 31217, United States
Skin Care Research, Inc

Hollywood, Florida, 33021, United States
Skin Specialists, P.C

Omaha, Nebraska, 68144, United States
Solutions Through Advanced Research

Jacksonville, Florida, 32256, United States
Texas Dermatology and Laser Specialists

San Antonio, Texas, 78218, United States
Total Skin and Beauty Dermatology Center, PC

Birmingham, Alabama, 35205, United States
UConn Health

Farmington, Connecticut, 06030-2840, United States
University of California Davis (UC Davis) Comprehensive Cancer Center

Sacramento, California, 95816, United States
Virginia Clinical Research, Inc.

Norfolk, Virginia, 23502, United States
Wallace Medical Group, Inc.

Los Angeles, California, 90056, United States
Washington University School of Medicine

St Louis, Missouri, 63110, United States
Wilmington Health Family Medicine

Wilmington, North Carolina, 28411, United States

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