Heart check: cancer Drug's effect on healthy volunteers revealed

NCT ID NCT05630274

First seen Nov 01, 2025 · Last updated Apr 28, 2026 · Updated 31 times

Summary

This study looked at how a single dose of the cancer drug Selpercatinib (LOXO-292) affects the heart's electrical activity in 32 healthy adults. Participants took the drug, a placebo, or a positive control in random order, and had their heart rhythm measured by ECG. The goal was to see if the drug changes the QT interval, a measure of heart electrical recovery. No treatment benefit was expected or provided.

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Contacts and locations

Locations

  • Celerion

    Tempe, Arizona, 85283, United States

Conditions

Explore the condition pages connected to this study.