New pill shows promise for hard-to-treat blood cancers

NCT ID NCT04849416

First seen Feb 06, 2026 · Last updated Apr 24, 2026 · Updated 5 times

Summary

This study tested an oral drug called LOXO-305 in 87 Chinese adults with chronic lymphocytic leukemia, small lymphocytic lymphoma, or non-Hodgkin lymphoma whose cancer had returned or not responded to prior treatments. The main goal was to see how many patients had their tumors shrink or disappear. The study lasted up to four years and focused on safety and effectiveness.

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Contacts and locations

Locations

  • Affiliated Hospital of Hebei University

    Baoding, Hebei, 71066, China

  • Beijing Cancer hospital

    Beijing, Beijing Municipality, 100142, China

  • Hainan General Hospital

    Haikou, Hainan, 570311, China

  • Harbin Medical University Cancer Hospital

    Harbin, Heilongjiang, 150081, China

  • Henan Cancer Hospital

    Zhengzhou, Henan, 450008, China

  • Hunan Cancer Hospital

    Changsha, Hunan, 410013, China

  • Institute of hematology&blood disease hospital

    Tianjin, Tianjin Municipality, 300020, China

  • Nanjing Drum Tower Hospital The Affiliated Hospital of Nanjing University Medical School

    Nanjing, Jiangsu, 210000, China

  • Shanghai East Hospital

    Shanghai, 200120, China

  • Sichuan Cancer Hospital

    Chengdu, Sichuan, 610041, China

  • Southern Medical University Nanfang Hospital

    Guangzhou, Guangdong, 510515, China

  • Sun Yat-sen University Cancer Center

    Guangzhou, Guangdong, 511400, China

  • The First Affiliated Hospital of Henan University of Science &Technology

    Luoyang Shi, Henan, 471003, China

  • The First Affiliated Hospital of Soochow University

    Suzhou, Jiangsu, 215066, China

  • The First Hospital of Jilin University

    Changchun, Jilin, 130021, China

  • Tianjin Medical University Cancer Institute and Hospital

    Tianjin, Tianjin Municipality, 300060, China

  • Wannan Medical College Yijishan Hospital

    Wuhu, Anhui, 241001, China

  • Xi'an International Medical Center Hospital

    Xi'an, Shaanxi, 710126, China

  • Xiangya Hospital Central South University

    Changsha, Hunan, 410008, China

  • Xingtai People's Hospital

    Xingtai, Hebei, 054031, China

  • Xinjiang Medical University Cancer Hospital - Urumqi

    Ürümqi, Xinjiang, 830000, China

  • Zhejiang Cancer Hospital

    Hangzhou, Zhejiang, 310022, China

Conditions

Explore the condition pages connected to this study.