CHRONIC KIDNEY DISEASE

This study is testing whether an experimental drug called ABP-671 can help protect kidney function in people who have both chronic kidney disease and high uric acid levels. About 75 participants will receive either the drug or a placebo for 28 weeks while researchers measure chan…

This study tests whether community health workers can help people better manage multiple chronic conditions like diabetes, high blood pressure, and heart disease. 300 adults with at least two chronic health conditions will work with trained health coaches for 9 months to develop …

This study is testing if a weekly injection called survodutide can help protect the kidneys in people with chronic kidney disease (CKD). It will involve 120 adults with CKD who have high levels of protein in their urine, a sign of kidney damage. The main goal is to see if the tre…

This early study is testing whether a special ultrasound device, called NEFRONIX, can help improve kidney function in people with chronic kidney disease (CKD). About 20 participants will have the device applied to their kidneys three times a week for four weeks. Researchers will …

This study tests whether a virtual meeting with a nurse before a doctor's visit can help people with diabetes and early kidney disease. The nurse provides education, motivation, and connects people to support services. Researchers want to see if this approach helps patients bette…

This study is testing whether a daily gut health supplement can help reduce chronic inflammation and improve digestive symptoms in adults with moderate to severe chronic kidney disease who are not yet on dialysis. About 100 participants will take either the supplement (containing…

This study is testing a new program that combines AI-guided community exercise with continuous glucose monitoring for adults who have both knee osteoarthritis and obesity. The main goal is to see if this approach helps control blood sugar levels. Researchers will also track chang…

This study is testing if a sodium bicarbonate enema can help adults with chronic kidney disease (CKD). The goal is to see if it can relieve constipation and reduce the buildup of harmful waste products in the body. Researchers will measure toxin levels in the blood before and aft…

This study is testing a new setting on a home dialysis machine called FlexPoint. It will compare different machine settings to see which one best removes waste and excess fluid from the blood of people with kidney failure. The goal is to see if adjusting these settings can make h…

This study is testing if a medicine called finerenone, already used for kidney disease, can also protect the eyes and slow vision loss. It will involve 40 adults with chronic kidney disease. Researchers will use eye scans to measure changes in the retina over six months to see if…

This study is testing a new program where specially trained community pharmacists can prescribe medications to help slow kidney damage in people with type 2 diabetes. It focuses on adults who do not have a regular family doctor. Researchers will compare health outcomes for 120 pe…

This study is testing whether adding probiotic supplements to standard anemia treatment helps kidney disease patients on dialysis. Researchers want to see if probiotics make the main anemia drug (erythropoietin) work better for 80 adult patients. Participants will take either the…

This study is testing a program called 'Moxie' designed to help people with chronic heart, kidney, or diabetes conditions manage their health better after leaving the hospital. It will enroll 9,000 adults in Alberta to see if receiving weekly health information by mail and/or let…

This study is testing a new support package for older adults who have two or more long-term health problems, like high blood pressure, diabetes, or arthritis. The package includes digital tools, personalized guidance, and ongoing support to help manage their health. Researchers w…

This study aims to create a safety system so people with type 1 diabetes and mild-to-moderate kidney disease can use a medication called sotagliflozin, which protects the heart and kidneys, without raising their risk of diabetic ketoacidosis (DKA). Researchers will have 80 partic…

This study aims to create and test a practical system for hospitals to offer and give recommended vaccines to adults with chronic diseases or weakened immune systems. It will involve 1,500 patients, offering vaccines during their hospital visits or stays. The goal is to see if th…

This study is testing whether two different amino acid supplements are practical and helpful for improving muscle mass and strength in people with advanced kidney disease who are experiencing muscle loss. It will involve about 20 participants who are not on dialysis. The goal is …

This study aims to see if two simple, non-drug treatments can help people on kidney dialysis who get painful muscle cramps during their treatment. Researchers will compare vibration massage and gentle stretching exercises to usual care to see which better reduces cramp pain, shor…

This study is testing a new mobile app designed to help adults in Vietnam with advanced chronic kidney disease better manage their symptoms. The app will allow 60 participants to track their symptoms and learn strategies to cope with them over 6 weeks. The main goal is to see if …

This study aims to learn more about chronic kidney disease by observing patients in real-world settings. It will follow 300 adults with moderate kidney disease to see if a common class of drugs (SGLT2 inhibitors like empagliflozin) helps slow the decline of kidney function. The s…

This study aims to understand the connection between chronic kidney disease and gum disease (periodontitis). Researchers want to see if a diet that promotes inflammation makes gum problems worse in people with kidney disease. They will observe 100 adults with kidney disease, chec…

This study aims to understand why some people in Spain face unfair barriers to getting a life-saving kidney transplant, even though the country is a world leader in transplants. Researchers will survey and interview about 3,000 patients and healthcare professionals to identify th…

This study aims to understand how different treatments for blocked heart arteries affect kidney health over many years. Researchers will look back at the medical records of over 1,700 patients who received medication, stents, or bypass surgery. The goal is to see if one treatment…

This study aims to understand how potassium from fresh foods like fruits and vegetables affects the body differently than potassium from processed foods in people with advanced chronic kidney disease. Researchers will provide 48 participants with four different 10-day diets to me…

This study aims to see if a simple calculation based on two common blood tests (triglycerides and glucose) can predict insulin resistance in people with early-stage kidney disease who are also at risk for diabetes. Researchers will enroll 60 adults without diabetes to test this m…

This study aims to understand the relationship between urinary function (like bladder control and flow) and the development of other common age-related health problems, such as diabetes, heart disease, and high blood pressure. It will follow 500 Beijing residents aged 60 and olde…

This study aims to find out how common early artery disease is in people who have both type 2 diabetes and chronic kidney disease. Researchers will use a simple, safe neck ultrasound to check for early signs of artery hardening in 96 participants. The goal is to gather informatio…