Vitamin B3 supplement could boost energy in kidney disease

NCT ID NCT07693543

First seen Jul 09, 2026 · Last updated Jul 16, 2026 · Updated 3 times

Summary

This study tests whether a dietary supplement called nicotinamide riboside (a form of vitamin B3) can be safely taken by adults with moderate chronic kidney disease. The main goal is to see if it's feasible for participants to take the supplement daily and complete study procedures. The study also explores whether NR affects markers of cellular energy, blood vessel function, and physical function. Participants will take NR and a placebo in random order, each for 12 weeks, without knowing which they are taking.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
nicotinamide riboside (a form of vitamin B3)
What this could lead to
If successful, this could point toward a dietary supplement that supports energy metabolism and kidney health in people with chronic kidney disease.
What could go wrong
This is a small, early-phase pilot study focused on feasibility, not proof of effectiveness. The supplement may not improve kidney function or could cause side effects.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Altman Clinical and Translation Research Institute

    San Diego, California, 92093, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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