Could a month of hydrocortisone protect kidneys after adrenal surgery?
NCT ID NCT07558811
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether giving hydrocortisone for one month after adrenal gland removal can slow kidney function decline in patients with primary aldosteronism and chronic kidney disease. About 90 adults will be randomly assigned to receive either hydrocortisone or standard care. The main goal is to compare changes in kidney function one year after surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- hydrocortisone
- What this could lead to
- If it works, this could point toward a simple way to protect kidney function after adrenal surgery in patients with primary aldosteronism and chronic kidney disease.
- What could go wrong
- This is a small, early-phase trial with only 90 participants, so results may not apply broadly. The benefit of short-term hydrocortisone is uncertain and may not outperform standard care.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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