Could a month of hydrocortisone protect kidneys after adrenal surgery?

NCT ID NCT07558811

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether giving hydrocortisone for one month after adrenal gland removal can slow kidney function decline in patients with primary aldosteronism and chronic kidney disease. About 90 adults will be randomly assigned to receive either hydrocortisone or standard care. The main goal is to compare changes in kidney function one year after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

hydrocortisone

What this could lead to

If it works, this could point toward a simple way to protect kidney function after adrenal surgery in patients with primary aldosteronism and chronic kidney disease.

What could go wrong

This is a small, early-phase trial with only 90 participants, so results may not apply broadly. The benefit of short-term hydrocortisone is uncertain and may not outperform standard care.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

chronic kidney disease hyperaldosteronism primary aldosteronism

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.