Polycystic ovary syndrome

This study tests a combination of herbs (Melats P) in 116 women aged 18-40 with PCOS and insulin resistance. The goal is to see if the treatment can restore regular periods and ovulation, helping overcome infertility. Participants will be monitored for 4 months using ultrasound a…

This study tested a herbal extract from a Himalayan plant (Nepeta adenophyta) in 116 women with PCOS. Participants took either the herb, the standard drug metformin, or both for 4 months. The goal was to see if the herb could help restore regular menstrual cycles and improve meta…

This study looked at whether inositol, a natural supplement, can improve ovulation in women with polycystic ovary syndrome (PCOS) who did not respond to the fertility drug letrozole. 36 women aged 18-35 took part. The researchers compared inositol to metformin, another common tre…

This study tested two approaches to help women with PCOS who did not ovulate after standard letrozole treatment. One group took letrozole for 7 days instead of 5, and the other took letrozole plus inositol. The goal was to see which method led to more ovulations and pregnancies. …

This study tested whether adding dapagliflozin (a diabetes drug) or metformin to the standard fertility drug letrozole helps women with polycystic ovary syndrome (PCOS) ovulate and become pregnant. 200 women participated. The goal was to see if these combinations improve ovulatio…

This study looked at whether a traditional Chinese herbal mixture (Zishen Qingre Lishi Huayu) can help women with polycystic ovary syndrome (PCOS) ovulate more regularly. The trial involved 126 women aged 20 to 40 and used a double-blind, placebo-controlled design to measure ovul…

This study looked at whether fenugreek seed powder could help young women (ages 15-25) with Polycystic Ovary Syndrome (PCOS). The goal was to see if it could improve hormone balance and ovulation. 70 women took part. The results could offer a low-cost, natural option for managing…

This pilot study tested whether adding krill oil to standard metformin therapy improves metabolic health in women with PCOS and obesity. Fifty-four women were split into three groups: metformin alone, krill oil alone, or both together for 8 weeks. Researchers measured changes in …

This study tested whether adding dapagliflozin (a diabetes drug) or metformin to the standard ovulation drug letrozole helps women with PCOS ovulate and become pregnant more often. 500 women aged 20-40 with PCOS and infertility took part. The goal was to see if these combinations…

This study tested whether combining two fertility drugs (letrozole and clomiphene) works better than letrozole alone for women with PCOS who did not ovulate with clomiphene alone. 42 women aged 20-40 took part. The goal was to see which treatment led to more mature eggs and thick…

This study compared two lifestyle approaches—intermittent fasting (eating only during an 8-hour window) and resistive exercise (like weight training)—for improving insulin resistance in 72 obese women with polycystic ovary syndrome (PCOS). The goal was to see which method is more…

This study compared two hormone protocols for women with high ovarian response undergoing IVF. One used progesterone (dydrogesterone) and the other used a GnRH antagonist. The goal was to see which approach leads to more eggs retrieved and higher pregnancy rates. 200 women partic…

This study looked at whether acupuncture (personalized or fixed) or the drug letrozole could help women with polycystic ovary syndrome (PCOS) have a baby. Over 1,100 women took part, receiving treatment for 16 weeks. The main goal was to see which approach led to more live births…

This study looked at whether a type of diabetes drug called SGLT2 inhibitors can help women with Polycystic Ovary Syndrome (PCOS) better than the standard drug metformin. The researchers believe these drugs may work by reducing inflammation in the body. The study involved 82 wome…

This study looked at 68 women with PCOS and high AMH levels who were trying to get pregnant. Researchers compared two pretreatment approaches: one group received a standard hormone pill plus metformin, while the other group also received myoinositol. After three months of pretrea…

This study tested two diabetes drugs, pioglitazone and metformin, in 60 women with insulin-resistant PCOS. Each woman took one drug daily for three months. Researchers measured changes in insulin resistance, waist-to-hip ratio, and hormone levels to see which drug worked better.

This study compared the effects of liraglutide and metformin in 150 obese women with polycystic ovary syndrome (PCOS) who were trying to conceive. Researchers measured weight loss, hormone levels, and metabolic changes. The goal was to see if liraglutide offers better results tha…

This study looked at two dietary supplements, myo-inositol and d-chiro-inositol, to see which one better improves insulin resistance in infertile women with PCOS. 80 women took one of the two supplements for three months. The goal was to see if one is not worse than the other at …

This study tested whether umbilical cord stem cells and their secretions (secretomes) can help women with polycystic ovary syndrome (PCOS) who also have insulin resistance. 44 women received either stem cells, secretomes, both, or a control treatment. The goal was to see if these…

This study tested whether two natural supplements (acetyl L-carnitine and myo/chiro-inositol) can help women with PCOS ovulate and become pregnant. 120 women aged 18-35 with PCOS-related infertility took part. The goal was to see if these supplements improve ovulation and pregnan…

This study looked at 192 women with PCOS to see which treatment works best for improving insulin resistance and other symptoms. Participants were randomly assigned to take metformin, inositol, follow a calorie-restricted diet, or combine all three for 12 weeks. The goal was to fi…

This study compared myo-inositol and metformin for helping women with polycystic ovary syndrome (PCOS) lose weight. Sixty women took either myo-inositol or metformin for three months. The main goal was to see which drug reduced body mass index (BMI) more effectively.

This study looked at a standardized way to diagnose and treat polycystic ovary syndrome (PCOS) in primary care. Researchers worked with 227 women aged 18-50 to see if a structured care plan, including lifestyle changes and prebiotic supplements, could improve insulin resistance a…

This study looked at two different doses of a birth control pill (drospirenone-ethinyl estradiol) in 60 women with PCOS. The goal was to see which dose better lowers a hormone marker called free androgen index. Participants took either a 20µg or 30µg dose daily for 3 months, and …

This study tested whether inositol, a natural dietary supplement, can lower high testosterone levels in women with polycystic ovary syndrome (PCOS). 154 women took either a placebo or one of three doses of inositol powder for a set period. Researchers measured changes in testoste…

This study looked at 120 overweight women with PCOS trying to conceive naturally. Half took myo-inositol alone, the other half took myo-inositol plus metformin for six months. The goal was to see which approach led to more confirmed pregnancies and had fewer side effects. The res…

This study tested whether a step-up dose of the drug letrozole helps women with PCOS ovulate better than the standard low dose. 70 women took either the step-up or standard dose for up to 3 menstrual cycles. Researchers tracked follicle growth, uterine lining thickness, and pregn…

This study looked at whether using a contraceptive vaginal ring (NuvaRing) for 16 weeks affects the risk of metabolic syndrome in overweight or obese women with polycystic ovary syndrome (PCOS). Researchers enrolled 22 participants and measured changes in blood pressure, waist si…

This study tested whether taking curcumin (from turmeric) daily for 12 weeks could improve cholesterol, blood sugar, hormones, and liver health in women with both PCOS and nonalcoholic fatty liver disease. 74 women participated in a double-blind, placebo-controlled trial. The goa…

This study looked at whether a supplement called NMN can help women with polycystic ovary syndrome (PCOS). The researchers measured changes in hormone levels, ovarian health, and menstrual cycles. 88 women aged 20-40 with a BMI under 25 took part. The goal was to see if NMN could…

This completed study tested whether the diabetes drug semaglutide (Rybelsus) could help 60 adolescent girls with PCOS and obesity reduce liver fat and improve insulin sensitivity, compared to a weight loss diet. Participants took a daily oral tablet for 4 months or followed a pre…

This study looked at how metformin, a diabetes medicine, affects hormone levels in women with polycystic ovary syndrome (PCOS). 77 women aged 20-40 with PCOS took part. Researchers measured changes in key hormones like luteinizing hormone and testosterone after treatment.

This study looked at whether taking birth control pills every day for 6 months (continuous) works better than the usual 3-weeks-on, 1-week-off schedule for women with Polycystic Ovary Syndrome (PCOS). The goal was to see which approach lowers testosterone levels and improves symp…

This study looked at 240 overweight or obese women with PCOS to see if birth control pills, metformin, or a combination of both is best for reducing metabolic syndrome—a cluster of conditions that raise the risk for diabetes and heart disease. Participants took one of the three t…

This study tested whether the drug metformin can improve fertility-related hormones and reduce inflammation in women with polycystic ovary syndrome (PCOS). 110 women with PCOS took metformin for 8 weeks and provided blood samples and symptom reports. The goal was to see if metfor…

This study looked at whether a diet-only or a diet-plus-exercise program works better for obese women with polycystic ovary syndrome (PCOS). Twenty-seven women were split into two groups: one received dietary advice, the other got both diet and personalized exercise recommendatio…

This study tested whether adding cabergoline to the standard drug letrozole helps women with PCOS ovulate more often. One hundred women took either letrozole alone or letrozole plus cabergoline. Researchers tracked ovulation using ultrasound starting on day 10 of the menstrual cy…

This study looked at whether time-restricted eating (eating only during certain hours) combined with a Mediterranean diet could help women with polycystic ovary syndrome (PCOS). Fifty-five women with PCOS and a BMI between 25-35 took part. The goal was to see if these diet change…

This study measured how common anxiety and depression are in adolescents with polycystic ovary syndrome (PCOS). 42 teens took a combined oral contraceptive daily for six months. Researchers tracked changes in depression scores to see if the pill improved mood along with PCOS symp…

This study looked at whether doing hatha yoga, with or without Zumba exercise, can improve symptoms in women with Polycystic Ovary Syndrome (PCOS). Fifty-four women aged 23-28 with PCOS took part. The researchers measured pain and anxiety levels to see if these activities helped.

This study tested whether a special supplement containing antioxidants and probiotics could improve egg quality in women with polycystic ovary syndrome (PCOS) undergoing IVF. Twenty women took either the supplement or a placebo (just folic acid) during their IVF cycle. Researcher…

This study tested whether daily text messages and small financial rewards could motivate overweight teens and young adults with prediabetes or type 2 diabetes to be more physically active. 75 participants wore a Fitbit and received different combinations of texts and incentives o…

This study looked at 100 women with Polycystic Ovary Syndrome (PCOS) to understand how the condition impacts their quality of life and mental health. Researchers examined factors like age, weight, how long it took to get a diagnosis, and history of anxiety or depression. Particip…

This study looked at 30 women with PCOS who had trouble ovulating. Researchers measured a hormone called AMH while giving low doses of FSH to see if a drop in AMH happens when an egg follicle starts to grow. The goal was to better understand why ovulation fails in PCOS, not to te…

This completed observational study at Uşak University examined 150 adults hospitalized in the endocrinology department. Researchers measured breathing, muscle strength, pain, fatigue, sleep quality, physical activity, balance, and nerve function. The goal was to better understand…

This study tested whether adding platelet-rich plasma (PRP) to lab dishes helps immature eggs from women with PCOS mature. Researchers tried three different PRP concentrations and found that 5% PRP worked best, leading to more mature eggs than standard methods. The study was smal…

This study aimed to find the best way to diagnose excess hair growth (hirsutism) and hair loss in women with PCOS. Researchers studied 1330 women to determine the most accurate scoring method. The goal is to improve diagnosis and understanding of these common symptoms.

This completed study used 2D and 3D ultrasound to measure uterine and endometrium volume in 648 women with PCOS or HPOD, two conditions that cause irregular periods. The goal was to see if these measurements could help tell the two disorders apart. The study did not test any trea…

This study measured levels of a protein called betatrophin in 90 adolescent girls with and without PCOS. Researchers wanted to see if betatrophin is linked to insulin resistance and body weight in PCOS. The goal was to better understand the metabolic problems that often come with…

This completed study looked at how ovulation disorders affect quality of life in nearly 1,000 women aged 18-45 with irregular periods. Participants filled out a 36-question survey covering physical, emotional, and social well-being. The goal was to compare two groups: those with …

This study looked at 300 women with different types of PCOS and healthy women to see if kidney function and urine protein levels differ. Researchers measured urine albumin-to-creatinine ratio and estimated glomerular filtration rate. The goal was to understand if certain PCOS typ…

This study created and tested a new questionnaire to measure both the severity of Polycystic Ovary Syndrome (PCOS) symptoms and the distress they cause. Researchers enrolled 227 women diagnosed with PCOS in Turkey. Participants completed online surveys, including the new inventor…

This study examined how common PCOS treatments (birth control pills and clomiphene citrate) affect the eyes. Researchers measured dry eye signs and retinal blood vessels in 60 women with PCOS and compared them to 30 healthy women. The goal was to see if these treatments cause cha…

This study looked at how polycystic ovary syndrome (PCOS) impacts women's sexual health. Researchers compared 84 women—some with PCOS and some without—using online questionnaires about sexual function, distress, body image, and mood. The goal was to help doctors better understand…

This study looked at 58 pregnant women with and without PCOS to understand how hormones like AMH and leptin might be passed to their babies. Researchers measured these hormones in the mother's blood during each trimester and in the placenta after birth. The goal was to see if hig…

This study used advanced MRI scans to look at the hypothalamus, a brain region that controls hormones, in women with PCOS. Researchers compared 52 women with and without PCOS to see if there were differences in brain structure and chemistry. The goal was to better understand how …

This early study tested whether giving a continuous infusion of kisspeptin, a natural hormone, could dampen the overactive reproductive signals seen in polycystic ovary syndrome (PCOS). Eight women with PCOS received the hormone for 24 hours, and researchers measured changes in t…

This completed study measured how common anxiety and depression are among 768 infertile Vietnamese women with polycystic ovary syndrome (PCOS). Researchers used standard questionnaires to screen for these conditions. The goal was to understand the mental health burden and identif…

This completed study looked at 70 adolescent girls with PCOS and 40 healthy teens to see if vitamin D levels are linked to metabolic problems like insulin resistance. Researchers measured vitamin D, blood sugar, cholesterol, and belly fat thickness using ultrasound. The goal was …

This study measured steroid hormone levels in 56 adolescents and young women with PCOS before and after 6 months of oral contraceptive treatment. Researchers used a precise lab method to track changes in hormones like testosterone. The goal was to better understand how birth cont…