Could diabetes meds help women with PCOS get pregnant?
NCT ID NCT07589075
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether adding dapagliflozin (a diabetes drug) or metformin to the standard ovulation drug letrozole helps women with PCOS ovulate and become pregnant more often. 500 women aged 20-40 with PCOS and infertility took part. The goal was to see if these combinations improve ovulation and pregnancy rates compared to letrozole alone.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Dapagliflozin and metformin (as add-on to letrozole)
What this could lead to
If successful, this approach could offer a new way to help women with PCOS ovulate and become pregnant more effectively.
What could go wrong
This is a completed phase 4 trial, but results are not yet published. The benefits may be modest, and side effects like urinary infections or gastrointestinal issues are possible with these drugs.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Gynecology and Reproductive department in Beni-Suef University Hospital
Banī Suwayf, 62517, Egypt