PCOS mystery: could a pregnancy hormone be the key to inherited risk?

NCT ID NCT03483792

Completed Knowledge-focused Sponsor: University Hospital, Lille Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at 58 pregnant women with and without PCOS to understand how hormones like AMH and leptin might be passed to their babies. Researchers measured these hormones in the mother's blood during each trimester and in the placenta after birth. The goal was to see if higher AMH levels in pregnancy could explain why daughters of women with PCOS are more likely to develop the condition.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this research could help explain why daughters of women with PCOS have a higher risk of developing the condition, pointing toward potential early interventions.
What could go wrong: This is a small, observational study that only measures hormone levels during pregnancy. It does not test any treatment, so it cannot directly lead to a cure or therapy on its own.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

polycystic ovary syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

POLYCYSTIC OVARY SYNDROME

Contacts and locations

Locations

Hôpital Jeanne de Flandres, CHU

Lille, France

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