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Could interval training and fasting tame PCOS insulin resistance?

NCT ID NCT07708766

Disease control Sponsor: Cairo University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 16, 2026 · Last updated Jul 17, 2026 · Updated 1 time

Summary

This study investigates whether combining high-intensity interval training (HIIT) with intermittent fasting (14-hour fast, 10-hour eating window) can reduce insulin resistance in obese women with polycystic ovary syndrome (PCOS). Participants will follow a supervised exercise program and a 1400-calorie diet during eating hours. The researchers will measure changes in body weight, waist and hip circumference, blood sugar, and insulin levels, as well as quality of life.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
high-intensity interval training and intermittent fasting diet
What this could lead to
If effective, this combination could offer a drug-free way to manage insulin resistance and improve quality of life in women with PCOS.
What could go wrong
This is a small, early-stage study with 50 participants, so results may not apply to all women with PCOS. The diet and exercise regimen may be hard to maintain long-term.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 50 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jul 2026

An estimate. Start dates often move.

Expected to finish

Jan 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 35 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Obese women with polycystic Ovarian Syndrome (PCOS) as clinically diagnosed by the gynecologist. * Their ages will be ranged from 20 to 35 years old. * Their body mass index will be ranged from 30-40 kg/m2. * Their waist/hip ratio will be \> 0.8. * All of them should have at least two criteria of the Rotterdam diagnostic criteria of PCOS. Exclusion Criteria: * Cushing syndrome, diabetes mellitus. * Thyroid dysfunction. * Hypothalamic amenorrhea, ovarian hyperplasia. * Respiratory, renal and liver dysfunction.

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Conditions

The condition(s) this trial relates to.

polycystic ovary syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Polycystic ovary syndrome

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

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Contacts and locations

Locations

  • Hager Tharwat Mohamed

    Cairo, Egypt

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