Metformin vs. lifestyle: which works better for PCOS?

NCT ID NCT06479434

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested whether the drug metformin can improve fertility-related hormones and reduce inflammation in women with polycystic ovary syndrome (PCOS). 110 women with PCOS took metformin for 8 weeks and provided blood samples and symptom reports. The goal was to see if metformin is more helpful than lifestyle changes alone for managing PCOS symptoms.

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Conditions

The condition(s) this trial relates to.

Insulin Resistance polycystic ovary syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • DBBS

    Karachi, Sindh, 74800, Pakistan