Teens with PCOS: do birth control pills help anxiety and depression?

NCT ID NCT07127458

Completed Symptom relief Sponsor: Ege University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study measured how common anxiety and depression are in adolescents with polycystic ovary syndrome (PCOS). 42 teens took a combined oral contraceptive daily for six months. Researchers tracked changes in depression scores to see if the pill improved mood along with PCOS symptoms.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: combined oral contraceptive (ethinylestradiol 30 µg + drospirenone 3 mg)
What this could lead to: If successful, this could show that oral contraceptives help ease anxiety and depression symptoms in teens with PCOS.
What could go wrong: This is a small, completed study with only 42 participants and no control group, so results may not apply to everyone. It also cannot prove cause and effect.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

anxiety disorder Depression polycystic ovary syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PCOS (POLYCYSTIC OVARY SYNDROME)

Contacts and locations

Locations

Izmir Bakircay University

Izmir, 35665, Turkey (Türkiye)

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