Could two common supplements tame PCOS hormone chaos?

NCT ID NCT07723443

Completed Disease control Sponsor: Al-Mustansiriyah University Source: ClinicalTrials.gov ↗

First seen Jul 23, 2026 · Last updated Jul 24, 2026 · Updated 1 time

Summary

This trial investigates whether one month of daily vitamin E, folic acid, or both can improve hormone profiles and reduce symptoms like excess hair growth in women with polycystic ovary syndrome (PCOS). Researchers will measure changes in key reproductive hormones and a protein called ezrin, which may play a role in the condition. The study includes over 200 women with PCOS and a healthy comparison group.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: vitamin E and folic acid supplements
What this could lead to: If successful, this could point toward a simple, low-cost supplement strategy to help manage hormone imbalances and symptoms like hirsutism in women with PCOS.
What could go wrong: This is a small, short-term study (one month) with no blinding or placebo control, so results may be weak or not generalizable. Supplements may not meaningfully change hormone levels or symptoms.

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Conditions

The condition(s) this trial relates to.

polycystic ovary syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PCOS (POLYCYSTIC OVARY SYNDROME)

Contacts and locations

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Locations

Kamal Al-Samarrai Specialized Hospital

Baghdad, Al-Rusafa, 10064, Iraq

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