PCOS (POLYCYSTIC OVARY SYNDROME)

This study tests whether taking letrozole for 10 days instead of the usual 5 days helps more women with PCOS ovulate and get pregnant. About 84 women aged 18-40 will be randomly assigned to one of the two treatment schedules. The main goal is to see if the longer course leads to …

This study is testing a 6-month low-glycemic, high-fiber diet in 56 women with PCOS living in remote Yunnan, China. The goal is to see if this culturally-adapted diet can improve insulin resistance, hormone levels, and menstrual regularity. Participants must have a BMI of 24 or h…

This study tests whether a comprehensive PCOS education and lifestyle modification program delivered through virtual group sessions can improve health-related quality of life and metabolic health in women with PCOS and obesity. Forty non-pregnant women aged 18-49 with PCOS and a …

This 12-week study at Ohio State University will test if a ketogenic diet or a mixed diet with ketone supplements can help women with PCOS have more regular periods and improve hormone balance. About 40 women aged 18-40 with PCOS will be randomly assigned to one of two groups. Th…

This study tests whether a combination of Myo-Inositol and Dioscorea Villosa can help teenagers aged 14-19 with irregular periods (too frequent, too rare, or absent). The goal is to see if the treatment makes cycles more regular. 20 teens with or without PCOS will take the supple…

This study looks at the genetic activity of cumulus cells (cells that surround eggs) from women with PCOS who are undergoing a special lab technique called CAPA-IVM. Researchers want to see if these cells' gene patterns can predict which eggs will develop into healthy embryos. Te…

This study looks at whether a physical activity program can help improve hormone health and reduce diabetes risk in girls ages 8 to 12 who are at higher risk for PCOS. About 40 girls will either get a full program with coaching and messages, or a lighter version with just message…

This study looks at inflammation markers in the blood of women with PCOS, with or without insulin resistance, compared to women without PCOS. Researchers want to see if certain inflammatory proteins are linked to metabolic problems. About 100 women aged 18-45 will take part. No t…

This study looks at three proteins in the blood—kisspeptin, ghrelin, and zonulin—to see if they can serve as early warning signs for insulin resistance in women with polycystic ovary syndrome (PCOS). Researchers will compare protein levels among 100 women aged 18-45: those with P…