Can a simple supplement tame PCOS hormones?

NCT ID NCT03864068

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether inositol, a natural dietary supplement, can lower high testosterone levels in women with polycystic ovary syndrome (PCOS). 154 women took either a placebo or one of three doses of inositol powder for a set period. Researchers measured changes in testosterone, insulin, and glucose tolerance to see if the supplement helps control the condition.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Inositol (a dietary supplement)

What this could lead to

If it works, this could point toward a simple, over-the-counter supplement to help manage hormone imbalances in women with PCOS.

What could go wrong

This is a small, early-phase trial with only 154 participants. The supplement may not significantly improve symptoms, and results may not apply to all women with PCOS.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

anovulation glucose intolerance Hyperandrogenism Insulin Resistance metabolic disease polycystic ovary syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Penn State College of Medicine, Penn State Milton S. Hershey Medical Center

    Hershey, Pennsylvania, 17033, United States

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States