Disease of the tendon

This study tested a drug called pexidartinib (TURALIO) in 9 Japanese adults with tenosynovial giant cell tumor (TGCT), a rare, non-cancerous growth in the joints that causes pain and limits movement. The goal was to see if the drug is safe and can shrink tumors in people whose tu…

This study tested whether platelet-rich plasma (PRP) can improve tendon healing in people with a torn rotator cuff. Forty adults having arthroscopic repair surgery were split into two groups: one received PRP during surgery, the other did not. Researchers compared tendon tissue s…

This study tested nilotinib, a drug originally used for leukemia, in 17 patients with relapsed or metastatic pigmented villonodular synovitis (PVNS) or related giant cell tumors. The goal was to see if the drug could stop tumor growth or improve symptoms. Results focused on how l…

This study looked back at 214 patients who had shoulder surgery using two specific devices (ToggleLoc and JuggerLoc) to reattach soft tissue to bone. The goal was to see if the devices helped the tissue heal properly and were safe. Results showed most patients had good healing wi…

This study looked at how well flu vaccines (seasonal and H1N1) work in 234 adults with autoimmune diseases like lupus or vasculitis, some of whom were on steroids or immunosuppressants. Researchers measured antibody levels three weeks after each shot to see if the vaccine provide…

This study tested an injection of stromal vascular fraction, a mixture of cells from the patient's own fat tissue, for patellar tendinopathy (jumper's knee). Thirty participants received the injection under ultrasound guidance. The goal was to see if it could improve symptoms and…

This study is working to create a reliable imaging test to find and measure problem areas in muscle and fascia tissue, known as myofascial pain. Researchers will use ultrasound and MRI to identify unique 'biosignatures' in 120 people with plantar fasciitis, Achilles tendinopathy,…

This study tested a Turkish version of the Johns Hopkins In-Room Independence Scale, which measures a patient's ability to move, use the toilet, and think clearly while in their hospital room. Researchers worked with 100 adults who had conditions like stroke, Parkinson's, or ampu…

This study looked at whether infrared thermography (a heat-sensing camera) can help diagnose patellar tendinopathy, a common knee injury in athletes. Researchers compared thermal images from 54 athletes—some with the condition and some healthy—to see if heat patterns and texture …

This study tested whether adding a nerve-stimulating technique (ultrasound-guided percutaneous neuromodulation) to standard treatments (electrolysis and eccentric exercises) helps athletes with jumper's knee. 26 adults aged 18-50 who played sports at least 3 times a week and had …

This study tested two different therapies for rotator cuff tendinopathy, a common cause of shoulder pain. Thirty-four patients received either blood flow restriction therapy or gua sha scraping, both combined with exercises, twice a week for six weeks. The goal was to see which a…

This study tested whether a structured eccentric training program—exercises that lengthen the muscle under load—could reduce pain and improve hand function in 25 adults with de Quervain's tendinopathy who had not gotten better with other treatments. Participants did the exercises…

This study tested a new exercise method called Tendon Neuroplastic Training (TNT) in 26 wrestlers with shoulder tendinopathy. TNT uses a smartphone metronome to pace exercises, aiming to improve brain-muscle control. The goal was to see if it could boost shoulder function, balanc…

This study looked at whether Pilates exercises can help people with Achilles tendinopathy, a condition causing pain and swelling in the back of the ankle. Researchers compared Pilates to standard eccentric exercises in 49 adults. The goal was to see if Pilates could reduce pain a…

This study tested a new, less invasive surgery for tennis elbow. 29 adults with chronic elbow pain received a water-jet procedure guided by ultrasound. Researchers measured pain and function changes over 12 months to see if the treatment helped.

This study tested whether low-intensity laser therapy can reduce shoulder pain caused by inflammation of the supraspinatus tendon. Forty adults with confirmed tendinopathy received laser treatment over three months. Researchers measured pain levels, shoulder movement, and quality…

This study tested a new injection treatment called PIT (using a sugar-water solution) against TENS (a mild electrical stimulation device) for people with shoulder pain. Thirty-two adults with ongoing shoulder pain received either PIT or TENS, plus exercises, over two weeks. The g…

This study tested a special injection made from donated placenta tissue in 20 people with long-lasting Achilles tendon pain that didn't get better with standard treatments like physical therapy. The goal was to see if the injection could reduce pain and improve function. Results …

This study looked at 80 people with painful calcium deposits in the shoulder tendon that didn't get better with standard care. All received a needle procedure to remove the deposits, and half also got an injection of their own platelet-rich plasma (PRP). The goal was to see if ad…

This study looked at whether adding a technique called tissue flossing (wrapping an elastic band around the lower leg and doing exercises) to standard heel-drop exercises can reduce pain and improve movement in people with Achilles tendinopathy. Thirty adults aged 20-45 with long…

This study looked at whether a video that teaches teens how fear and stress affect pain can help them recover from leg pain. 86 teens with leg pain for over a month took surveys and wore activity trackers. Half watched the special video, and all were followed for a year to see if…

This study tested whether using ultrasound to guide a needle-based treatment (pharmacopuncture) helps reduce shoulder pain more than the same treatment without ultrasound. Forty adults with moderate to severe shoulder pain from a torn or damaged tendon took part. The goal was to …

This study tested three treatments for long-term Achilles tendon pain: ozone injections, shock wave therapy, and standard exercise. 63 adults with persistent symptoms took part. The goal was to see which approach best reduces pain and improves daily function.

This study tested whether a hands-on technique called fascial manipulation can improve shoulder movement and body awareness in people with rotator cuff tendinitis. Thirty-two adults with persistent shoulder pain received the therapy twice a week for four weeks. Researchers measur…

This study tested whether secukinumab, an anti-inflammatory drug, can reduce pain and improve function in adults with moderate to severe rotator cuff tendinopathy (shoulder tendon pain) that didn't get better with standard treatments. 62 participants received either the drug or a…

This study looked at how common muscle and posture problems are in physiotherapy students and whether a special physiotherapy program could help. 44 students with back pain and muscle tightness received treatments like trigger point release, stretching, and joint mobilization. Th…

This study tested whether a shorter, 6-session exercise and education program could help people with gluteal tendinopathy, a common cause of hip pain in women over 40. 65 adults aged 35-70 with chronic hip pain took part. The goal was to see if a larger trial is possible, not to …

This study tested two common treatments for Achilles tendinopathy in 24 male football players aged 18-30: eccentric calf exercises (lowering the heel off a step) and wearing heel insoles. Over 12 weeks, researchers measured pain, ankle movement, and function. The goal is to find …

This study tested two different exercise programs in 66 adults with long-term shoulder pain caused by rotator cuff tendinopathy. One program focused on global postural reeducation, while the other used general aerobic exercises. The goal was to see which approach better reduces p…

This study tested whether adding low-energy shockwave therapy to a 12-week exercise program helps people with Achilles tendinopathy more than exercise alone. Forty-seven adults with pain and swelling in one Achilles tendon were randomly assigned to either exercise plus shockwave …

This study tested whether a combination of two medicines (etoricoxib and betamethasone) works better than just one (etoricoxib) for reducing pain from sudden joint swelling conditions like bursitis, tendinitis, or synovitis. About 89 adults with pain in their shoulder, elbow, kne…

This study tested whether combining two physical therapies—extracorporeal shockwave therapy and cryoflow (cold) therapy—can reduce shoulder pain and spasticity in stroke survivors with rotator cuff tendonitis. Thirty participants received either one therapy alone or both together…

This study tested two types of Kinesio Taping (a special elastic tape) in 42 people with patellar tendinopathy, also known as jumper's knee. The goal was to see if the tape could reduce pain and improve how the knee moves during walking, jogging, and other activities. Researchers…

This study tested whether wearing a forearm strap orthosis for 4 weeks could reduce pain and improve grip strength in 30 musicians who had forearm pain from playing their instruments. Participants used the strap during practice and daily activities. Researchers measured changes i…

This study tested a procedure called transcatheter arterial embolization (TAE) in 12 people with long-term elbow or foot pain that didn't get better with usual treatments like physical therapy or medication. The procedure uses tiny particles to block abnormal blood vessels though…

This study looked at adding tramadol, nefopam, or opioids to standard painkillers (paracetamol and ketoprofene) for adults recovering from shoulder surgery. 92 patients were enrolled, and their recovery quality was measured using a survey. The goal was to find the best oral pain …

This study compared two procedures for treating painful calcium buildup in the shoulder: barbotage (a needle-guided washout) and shock wave therapy. Sixty-three adults aged 30–60 with chronic shoulder pain were randomly assigned to one treatment. Researchers tracked pain levels a…

This study looked at whether letting patients control their own sedation during arm surgery under regional anesthesia leads to higher satisfaction compared to having an anesthesiologist control it. 70 adults having upper limb orthopedic surgery were randomly assigned to either pa…

This study tested whether a procedure called percutaneous needle electrolysis can help people with posterior tibial tendinopathy, a common cause of foot pain. 46 adults with pain for at least 3 months were split into two groups to compare the treatment against a control. Research…

This study tested whether teaching people about how pain works (pain neuroscience education) could improve shoulder pain and daily function. 42 adults with rotator cuff shoulder pain received either exercise alone or exercise plus pain education over 6 weeks. The goal was to see …

This study tests if a less invasive ultrasound-guided needle procedure can work as well as mini-open surgery for chronic tennis elbow that hasn't improved with rest or therapy. Sixty-four workers with persistent elbow pain will be randomly assigned to one of the two treatments. T…

This study tested whether adding a 'kinetic chain' exercise approach to standard treatment helps people with rotator cuff tendinopathy. 44 adults aged 40-65 with shoulder pain were split into two groups: one got standard care, the other added kinetic chain exercises. Researchers …

This study looked at how stretchy the skin and blood vessels are in people with Williams syndrome, a genetic condition that can cause heart problems. Researchers measured skin and pulse speed in 43 participants aged 5 to 70. The goal was to learn how these tissues change over tim…

This study translated the Generic Functional Index, a questionnaire that measures how well people can do daily activities, into Turkish. Researchers tested it with 200 adults who have muscle or joint problems to see if it is accurate and reliable. The goal is to give Turkish-spea…

This study looked at 719 people, including patients with autoimmune connective tissue diseases like myositis, their blood relatives, and healthy volunteers. Researchers collected blood samples and medical histories to find genetic and environmental factors that may trigger these …

This study tested whether giving general practitioners a simple, evidence-based guideline improves care for people with shoulder pain. 160 adults with shoulder pain took part in Norwegian GP clinics. Researchers measured pain, disability, and quality of life to see if the guideli…

This study used a special MRI technique to create detailed maps of the Achilles tendon in 121 adults. Researchers compared healthy volunteers to people with a type of arthritis called spondyloarthropathy, both with and without tendon pain. The goal was to better understand tendon…

This study looked at 29 people who had ACL surgery using their own hamstring tendons. Researchers used a special ultrasound to check how stretchy the healed tendons were and compared them to the healthy leg. They also tested leg muscle strength to see if tendon quality affects re…

This study looked at 489 patients who had Achilles tendon surgery to find out what factors lead to moderate-to-severe pain in the first 24 hours. Researchers created a prediction tool (nomogram) based on these risk factors. The goal is to help doctors identify high-risk patients …

This study used ultrasound to measure the thickness of certain hip muscles in 60 adults with hip pain on one side (Greater Trochanteric Pain Syndrome) and compared them to healthy people. The goal was to see if muscle thickness differs between the groups and to check for related …

This study looked at how people with patellar tendinopathy (a common knee overuse injury in sports) move their legs during side-cutting, compared to healthy individuals. Sixty participants—30 with the injury and 30 without—performed side-cutting tasks while motion capture cameras…

This study tested whether specially trained physiotherapists can safely diagnose and treat non-urgent muscle and joint pain in the emergency room, compared to standard care from doctors. 102 patients with back, neck, or shoulder pain were randomly assigned to either a physiothera…

This study looked at 40 adults who had to wear a splint or cast on their dominant hand for 6 weeks after an injury. The goal was to see if being forced to use the non-dominant hand actually improves its function. Researchers measured hand skills and disability levels to understan…

This study looked at 28 elite male ice hockey players to see how patellar tendinopathy (a common knee overuse injury) affects leg strength and power. Players were grouped by ultrasound findings into healthy, one-sided, or both-sided tendon issues. They performed leg strength test…

This study adapts a questionnaire called TENDINS-A into Spanish to better measure the severity of Achilles tendinopathy. About 100 Spanish-speaking adults with Achilles pain will fill out the questionnaire and repeat it after 48 hours. The goal is to ensure the tool is reliable a…

This study measured two newer blood markers (calprotectin and serum amyloid protein) alongside standard tests in 20 children with juvenile arthritis and related conditions. The goal was to see if these markers could better track disease flare-ups in everyday clinic visits. The st…

This completed study looked at 62 people with patellar tendon injuries to see if a special MRI technique called diffusion tensor imaging (DTI) can better measure tendon structure. Participants had MRI and ultrasound scans, did knee function tests, and filled out questionnaires. T…

This completed study compared how well people with complex regional pain syndrome (CRPS), people with other muscle or bone pain, and healthy individuals can imagine movements. Researchers used a questionnaire called the MIQ-RS to measure motor imagery skills. The goal was to see …

This study surveyed 116 adults with chronic pain at a rehabilitation clinic to understand how their pain beliefs, spiritual well-being, and attitudes toward complementary and alternative medicine are related. Participants filled out several questionnaires about their pain, mood, …

This completed study looked at 32 people with known genetic changes in connective tissue genes to better understand how these changes affect overall health. Participants underwent a range of medical tests and exams over 3-5 days. The goal was to gather information, not to test a …