Which painkiller works best after shoulder surgery? new study compares options

NCT ID NCT04110665

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at adding tramadol, nefopam, or opioids to standard painkillers (paracetamol and ketoprofene) for adults recovering from shoulder surgery. 92 patients were enrolled, and their recovery quality was measured using a survey. The goal was to find the best oral pain management strategy to improve recovery after same-day shoulder surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Tramadol, Nefopam, Morphine Sulfate, Oxycodone

What this could lead to

If successful, this could help doctors choose the best pain relief combination for shoulder surgery recovery.

What could go wrong

This is a small, completed Phase 4 trial with only 92 participants. Results may not apply to all patients, and opioids carry risks like dependence and side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

agnosia disease of the tendon Tendon Injuries

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHU de Nimes

    Nîmes, 30029, France