New imaging tests aim to pinpoint the source of mysterious muscle pain

NCT ID NCT06803056

Completed Diagnosis Sponsor: Ruth Chimenti Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jul 02, 2026 · Updated 2 times

Summary

This study is working to create a reliable imaging test to find and measure problem areas in muscle and fascia tissue, known as myofascial pain. Researchers will use ultrasound and MRI to identify unique 'biosignatures' in 120 people with plantar fasciitis, Achilles tendinopathy, or healthy tissue. The goal is to improve diagnosis and enable more personalized treatment for these common pain conditions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Diagnostic tests (clinical exam and ultrasound/MRI imaging)
What this could lead to: If successful, this could lead to better, more personalized diagnosis and treatment for myofascial pain conditions like plantar fasciitis and Achilles tendinopathy.
What could go wrong: This is an early-stage diagnostic study, not a treatment trial. The imaging biomarkers being developed may not prove accurate enough for widespread clinical use.

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Conditions

The condition(s) this trial relates to.

disease of the tendon Pain plantar fasciitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACHILLES TENDINOPATHY CONTROLS PLANTAR FASCIOPATHY

Contacts and locations

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Locations

University of Iowa Health Care

Iowa City, Iowa, 52242, United States

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