Nantes University Hospital
Clinical trials sponsored by Nantes University Hospital, explained in plain language.
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New program aims to fight tooth decay in kids with cleft conditions
Disease control CompletedThis study tested a special program to improve oral hygiene and dental care for children with cleft lip or palate. 60 children, aged 3 to 15, were randomly assigned to either receive standard care or an enhanced program with extra dentist visits and education. The goal was to see…
Phase: NA • Sponsor: Nantes University Hospital • Aim: Disease control
Last updated Apr 04, 2026 02:20 UTC
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New drug tested to help kidney transplants last
Disease control CompletedThis early-stage study tested a new drug called FR104 in 10 people receiving their first kidney transplant from a deceased donor. The main goal was to check if the drug was safe and how the body processed it, while also seeing if it could help prevent the body from rejecting the …
Phase: PHASE1, PHASE2 • Sponsor: Nantes University Hospital • Aim: Disease control
Last updated Apr 03, 2026 14:42 UTC
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Could a simple blood test replace liver biopsies for diabetes patients?
Diagnosis CompletedThis study aimed to see if two simple blood tests could effectively screen for liver scarring (fibrosis) in people with type 2 diabetes. It involved 722 participants with type 2 diabetes and a higher body weight. The results of the new blood tests were compared against the curren…
Phase: NA • Sponsor: Nantes University Hospital • Aim: Diagnosis
Last updated Apr 03, 2026 14:41 UTC
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New test aims to catch silent kidney damage after major heart operations
Diagnosis CompletedThis study aimed to create a better tool for spotting kidney injury early in patients recovering from major heart surgery. Researchers followed 400 patients to combine blood tests and health data into a single score. The goal was to help doctors identify at-risk patients sooner s…
Sponsor: Nantes University Hospital • Aim: Diagnosis
Last updated Mar 30, 2026 14:31 UTC
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New eye test could replace dozens of biopsies for esophagus check
Diagnosis CompletedThis study tested if a new, high-tech visual scan during an endoscopy could work as well as the standard method for monitoring Barrett's Esophagus, a condition that can lead to cancer. The standard method involves taking many small tissue samples (biopsies), which is time-consumi…
Phase: NA • Sponsor: Nantes University Hospital • Aim: Diagnosis
Last updated Mar 27, 2026 12:40 UTC
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Heel or no heel? study tests which bandage wrap works better for leg ulcers
Symptom relief CompletedThis study tested two ways to apply compression bandages for healing venous leg ulcers: one method covers the heel, and the other leaves it uncovered. Researchers wanted to see if leaving the heel uncovered is just as good at maintaining proper pressure and is more comfortable fo…
Phase: NA • Sponsor: Nantes University Hospital • Aim: Symptom relief
Last updated Apr 01, 2026 14:40 UTC
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Needle and injection combo tested for tough heel pain
Symptom relief CompletedThis small pilot study tested a two-part procedure for people with stubborn plantar fasciitis (heel pain) that didn't improve with standard treatments. Doctors used a needle to break up scar tissue and then injected a patient's own concentrated platelets to promote healing. The m…
Phase: NA • Sponsor: Nantes University Hospital • Aim: Symptom relief
Last updated Mar 30, 2026 14:30 UTC
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Lockdowns triggered major shifts in online gambling, study reveals
Knowledge-focused CompletedThis research project investigated how COVID-19 pandemic restrictions changed online gambling behaviors in France and Sweden. Researchers analyzed anonymous tracking data from 120,000 registered online gamblers to see if lockdowns led to more gambling or different patterns. The s…
Sponsor: Nantes University Hospital • Aim: Knowledge-focused
Last updated Apr 04, 2026 02:33 UTC
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Could pregnancy trigger rejection in transplant patients?
Knowledge-focused CompletedThis study looked at whether pregnancy increases the risk of organ rejection in women who have received lung transplants. Researchers examined 11 cases where women with lung transplants had pregnancies between 2012-2021. They compared genetic markers from the children, mothers, a…
Sponsor: Nantes University Hospital • Aim: Knowledge-focused
Last updated Apr 02, 2026 14:57 UTC
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Breathing tube safety test for obese surgery patients
Knowledge-focused CompletedThis study aimed to find the safest way to place a breathing tube in severely obese patients (BMI 35+) during surgery. It compared two common techniques used by anesthesiologists: placing the tube with or without using a face mask to provide oxygen first. The goal was to reduce c…
Phase: NA • Sponsor: Nantes University Hospital • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:11 UTC
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Scientists probe why heart surgery weakens Babies' immune defenses
Knowledge-focused CompletedThis study aimed to understand why heart surgery with a heart-lung machine might weaken the immune system in babies under 3 months old. Researchers measured specific substances in the blood before and after surgery to see if they were linked to reduced immune function. The goal w…
Sponsor: Nantes University Hospital • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:11 UTC
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Scientists map how injured legs walk differently
Knowledge-focused CompletedThis study aimed to understand how calf muscles and tendons work during walking in people who have had a stroke or a spinal cord injury, compared to healthy individuals. Researchers used ultrasound and motion analysis to measure how muscles and tendons stretch and move while 64 p…
Sponsor: Nantes University Hospital • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:33 UTC
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Surviving pneumonia may raise heart attack risk years later, major study finds
Knowledge-focused CompletedThis study looked at whether having pneumonia increases a person's long-term risk of developing serious heart problems like heart attacks or strokes. Researchers compared health records of 2 million people in France, including those who had pneumonia and similar people who did no…
Sponsor: Nantes University Hospital • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:31 UTC
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Scientists map the gambling brain: search for Addiction's fingerprint
Knowledge-focused CompletedThis study aimed to understand how gambling addiction affects thinking skills like decision-making and impulse control. Researchers compared brain function tests in 50 people with gambling disorder against healthy volunteers. The goal was to identify specific thinking problems th…
Phase: NA • Sponsor: Nantes University Hospital • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:19 UTC