Nantes University Hospital

This study looked at whether it is safe for people with multiple sclerosis to receive their natalizumab (Tysabri) infusions at home instead of at a hospital. Researchers compared serious side effects, quality of life, and costs over one year in 295 patients. The goal was to see i…

This study tested a new drug called FR104 in 10 people receiving a kidney transplant for the first time. The goal was to see if FR104 is safe and can help prevent the body from rejecting the new kidney. Researchers monitored side effects and kidney function over time.

This study tested three emergency treatments for dangerously high potassium levels (hyperkalemia) in 419 adults at emergency departments. It compared insulin/dextrose infusion, nebulized salbutamol, and a combination of both to see which lowers potassium most effectively within 6…

This study tested whether a special camera technique (virtual chromoendoscopy) can find pre-cancerous or early cancer spots in Barrett's esophagus better than the standard method of taking random biopsies. 110 adults with Barrett's esophagus were examined using both methods. The …

This study looked at whether two blood tests, eLIFT and FibroMeter, can accurately detect advanced liver fibrosis (scarring) in people with type 2 diabetes. The researchers compared these blood tests to a liver scan (FibroScan) and, in some cases, a liver biopsy. The goal is to f…

This study aims to create a new scoring system to detect acute kidney injury (AKI) early after heart surgery. AKI is a common and serious complication that can lead to longer hospital stays, chronic kidney disease, or even death. Researchers will combine blood and urine tests wit…

This study looked at two ways of applying compression bandages for people with open leg ulcers caused by vein problems. One method covered the heel, the other left it uncovered. The goal was to see which technique was more comfortable and kept the right amount of pressure to help…

This study tested a procedure that combines a needle to break up scar tissue with an injection of platelet-rich plasma (a concentrate from the patient's own blood) to treat stubborn heel pain from plantar fasciitis. Nineteen adults who had not improved with standard treatments li…

This study tested a set of natural dermo-cosmetic products (hand/foot serum, nail strengthener, dissolving oil, and gloves/slippers) in 20 multiple myeloma patients receiving anti-GPRC5D bispecific antibodies. The goal was to see if these products could prevent or reduce skin and…

This study examined how the COVID-19 pandemic affected online gambling behaviors in France and Sweden. Researchers analyzed data from 120,000 registered gamblers to see if lockdowns and stress led to more gambling. The goal was to understand changes in gambling habits and identif…

This completed study used health records from 2 million French adults to see if people who had pneumonia are more likely to develop heart disease, stroke, or other cardiovascular problems later on. Researchers compared pneumonia survivors to similar people without pneumonia. The …

This study looked for new blood markers that could show liver damage in people with anorexia nervosa. Researchers compared blood samples from 19 patients with and without signs of liver stress. The goal was to better understand how anorexia affects the liver, not to test a treatm…

This study looked at 346 adults who had a cardiac arrest outside the hospital. Doctors used an ultrasound within the first 12 minutes of CPR to see if the heart was still. The goal was to find out if a still heart on ultrasound can predict whether the person will survive or not. …

This study looked at 57 kidney transplant patients to see if high blood pressure is related to having too much fluid in the body. Participants measured their blood pressure and body fluid levels at home between 30 and 90 days after their transplant. The goal was to understand the…

This study looked at whether wearing a sleeve under a blood pressure cuff changes the reading. Researchers tested 75 intensive care patients who already had a special tube in their artery for precise blood pressure measurement. They compared readings taken on bare skin, over a th…

This study looked at 88 young children (3 months or younger) who had heart surgery with a heart-lung machine. Researchers measured certain proteins in the blood that can trigger an immune response, to see if they cause a temporary weak immune system after surgery. The goal was to…

This study looked at how the calf muscle and Achilles tendon move together during walking in people who have had a stroke or spinal cord injury, compared to healthy individuals. Researchers used ultrasound and 3D motion analysis to measure changes in muscle and tendon length. The…

This study looked at 11 children born to women who had lung transplants to see if shared immune markers (HLA types) between the child and the lung donor increase the mother's risk of organ rejection. Researchers collected cheek swabs from the children to compare their HLA types w…

This study looked at eye problems in 100 adults with atopic dermatitis (eczema) who were treated with tralokinumab. The main goal was to find out how often eye issues like conjunctivitis happen within the first 4 months of treatment. Researchers hope this will help doctors better…

This study aims to confirm that measuring two substances in the blood (FLT3L and IL-6) during the first round of chemotherapy can help predict how well patients with acute myeloid leukemia (AML) will do. Researchers will track 201 newly diagnosed AML patients across 25 French hos…

This study looked at how gambling disorder affects thinking and decision-making. Researchers compared 50 people with gambling disorder to healthy volunteers using brain tests. The goal was to find specific mental weaknesses that could be improved with cognitive training. No treat…

This study looked at 725 severely obese adults (BMI 35 or higher) to find the safest way to insert a breathing tube before surgery. Researchers compared giving oxygen through a face mask during the procedure versus not using a mask. The goal was to see which method causes fewer c…

This study measured how common liver scarring (fibrosis) is in people with anorexia nervosa. Researchers used a special ultrasound device called Fibroscan to check the liver stiffness of 43 patients admitted to a hospital in France. The goal was to better understand liver health …

This study tested whether a special oral hygiene program helps children with cleft deformities keep their teeth and gums healthier. About 60 children aged 3 to 15 took part. Researchers measured tooth decay and gum health to see if the program made a difference.

This study looked at how people with Alzheimer's disease or a type of frontotemporal dementia recall personal memories. Researchers analyzed whether memories were specific events or more general. The goal was to better understand memory loss patterns, not to test a treatment. 39 …

This study looked at the bacteria living in the lungs of 82 healthy volunteers scheduled for non-lung surgery. Researchers used advanced techniques to analyze both the bacteria and the immune cells in the lungs. The goal was to create a detailed atlas of how the lungs' natural ba…