Clot-Busting device could change stroke care
NCT ID NCT02880579
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at how well a mechanical device works to remove blood clots from the brain during a stroke. Researchers followed 230 adults who had a stroke within the previous 8 hours and received the procedure. The goal was to see if the treatment helps patients recover and reduces long-term disability.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- mechanical thrombectomy device
- What this could lead to
- If successful, this could confirm mechanical thrombectomy as a standard treatment for certain types of stroke, helping more patients recover with less disability.
- What could go wrong
- This is an observational analysis of existing practice, not a randomized trial. Results may not prove the procedure is better than other treatments, and risks like bleeding or vessel damage remain.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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230 people
The number who actually took part.
- Start date
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May 2013
- Finished
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Mar 2015
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
200 consecutive patients admitted to a stroke unit for cerebral infarction treated by thrombectomy included (with or without fibrinolysis by intra venous) prospectively over a period of 1 year and 3 months followed for clinical neurological assessment (primary endpoint) .
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Signature of the information notice by the patient or his legal representative * Age\> 18 years * Clinical and imaging consistent with ischemic stroke whose symptoms start back within 8h * Thrombosis (TICI 0 or 1) of the carotid T, M1, M1-M2 bifurcation of the basilar artery occlusion in TANDEM ACI / M1. Exclusion Criteria: * Pregnant or lactating women * Rapid improvement of NIHSS (gain of more than 4 points) between two pre-treatment assessments. * ASPECT score \<7 on the scanner or \<5 on the diffusion-weighted imaging (DWI) * Intracranial hemorrhage on imaging * Inability of clinical evaluations at 3 months * extensive lesions of the brain stem (the presence of a complete section of the brainstem hyperintense b1000) * 0 Refusal to participate in the study
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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CHU de Nantes
Nantes, 44093, France