Gait analysis sheds light on joint damage in moderate hemophilia
NCT ID NCT04024176
First seen Sep 14, 2026 · Last updated Sep 15, 2026 · Updated 1 time
Summary
Researchers at Nantes University Hospital are studying how joint damage from bleeding affects walking in adults with moderate hemophilia. About 24 participants will have their gait measured with motion capture and force platforms during a single visit. The study also collects clinical, imaging, and blood data to build a full picture of joint health. The goal is to understand whether moderate hemophilia leads to subtle walking problems that standard care might miss.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- quantified gait analysis
- What this could lead to
- If the study finds links between joint damage and walking problems, it could help doctors decide whether moderate hemophilia needs closer monitoring or earlier treatment.
- What could go wrong
- The study is small and observational, so it cannot prove cause and effect. It may not capture enough detail to change care, and results may not apply to children or people with severe hemophilia.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
24 people
The number who actually took part.
- Started
-
Nov 2019
- Finished
-
Sep 2020
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Have moderate Hemophilia A or B. * Have understood the protocol and signed its consent to participate. * Patient able to perform a walking test. * Patient affiliated to a social security system Exclusion Criteria: * Pregnant women * Minor * Majors under guardianship or curatorship * Refusal to participate; * Amputee of a lower limb * Need for technical walking assistance (walking sticks, walker,...). * Extensive dermatitis of the lower limbs (need for sensor installation for gait analysis); * Known NYHA (New York Heart Association) grade III or IV heart failure (resting dyspnea); * Unstable angina or myocardial infarction within three months of inclusion * Known severe respiratory disease; * Parkinson's disease, hemiplegia or paraplegia * Patient unable to understand the objectives or instructions of the study * Intercurrent pathology likely to modify walking abilities
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Arthropathy are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Department of Physical Medicine and Locomotive Rehabilitation (Nantes University Hospital)
Nantes, France
-
Department of Physical Medicine and Neurological Rehabilitation (Nantes University Hospital)
Nantes, France
-
Regional Hemophilia Treatment Centre (Nantes University Hospital)
Nantes, France
-
Rheumatology department (Nantes University Hospital)
Nantes, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Which injection eases arm pain better: steroid or Anti-Inflammatory?
- New study will track how well custom joint implants work over 5 years
- Vibration vs. cooling spray: which eases injection pain best?
- Could a tiny dose of radiation soothe immunotherapy joint pain?
- Rare disease CACP syndrome under the microscope: new study aims to unlock its secrets
- Can virtual reality ease stress after joint replacement? new study tests a High-Tech approach