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New scope technique could catch esophagus cancer earlier

NCT ID NCT05229783

Diagnosis Sponsor: Nantes University Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a special camera technique (virtual chromoendoscopy) can find pre-cancerous or cancerous spots in Barrett's esophagus better than the standard method of taking random biopsies. 110 adults with Barrett's esophagus took part. The goal was to see if the new method could replace the old one and improve detection of serious changes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

110 people

The number who actually took part.

Started

May 2022

Finished

Feb 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male or Female with Age above ≥ years old; * Female of childbearing potential must use appropriate method(s) of contraception during the clinical trial (i.e.: Intrauterine Device, pill, implant,sexual abstinence); * Dysplastic Barrett's Esophagus preferably labelled "flat mucosal dysplasia"; * Patient requiring esophageal endoscopy as part of their regular monitoring; * Affiliated to social security; * Patient received Patient Information Form and accepted to participate to the study. Exclusion Criteria: * Previously treated Barrett's Esophagus; * Known invasive esophageal adenocarcinoma; * Contraindication to general anesthesia; * Ongoing clopidogrel or anticoagulant therapy or coagulation disorder (platelet count \< 50 000/mm3, Prothrombin time ratio \<50%); * Poor general health status precluding subsequent follow up of Barrett's Esophagus ; * For female: pregnancy or breastfeeding; * Adults under a legal protection regime (guardianship, trusteeship, "under judicial protection"). * Ongoing participation in another study requiring an intervention on Barrett's Esophagus during patient's participation in Converse study

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Conditions

The condition(s) this trial relates to.

Barrett esophagus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Barrett esophagus

Contacts and locations

Locations

  • Amiens University Hospital

    Amiens, 80054, France

  • Besançon University Hospital

    Besançon, 25030, France

  • Bordeaux University Hospital

    Bordeaux, 33604, France

  • Brest University Hospital

    Brest, 26609, France

  • Limoges University Hospital

    Limoges, 87000, France

  • Lyon University Hospital

    Lyon, 69003, France

  • Nancy University Hospital

    Nancy, 54511, France

  • Nantes University Hospital

    Nantes, 44093, France

  • Nice University Hospital

    Nice, 06202, France

  • Poitiers University Hospital

    Poitiers, 86021, France

  • Private Bercy clinic

    Charenton, 94220, France

  • Public Assistance - Paris hospitals - Cochin hospital

    Paris, 75014, France

  • Public Assistance- Paris Hospitals - Georges Pompidou European Hospital

    Paris, 75015, France

  • Rennes University Hospital

    Rennes, 35033, France

  • Sainte Barbe Clinic

    Strasbourg, 67000, France

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