BARRETT ESOPHAGUS

This study aims to find the best approach for managing Barrett's esophagus with low-grade dysplasia, a condition that can sometimes lead to esophageal cancer. Researchers are comparing two common strategies: regular monitoring with camera exams and biopsies versus procedures that…

This study is testing whether a simple 'sponge-on-a-string' device can accurately detect Barrett's esophagus and early esophageal cancer. The goal is to create an easier screening method that doesn't require a full endoscopy procedure. Researchers will enroll about 1,550 adults a…

This study is testing a simple, swallowable sponge capsule called EsophaCap to collect cell samples from the esophagus and stomach. Researchers aim to find biological markers that can identify very early signs of Barrett's esophagus, esophageal cancer, and stomach cancer. The goa…

This study is testing a simple, swallowable sponge device called Cytosponge as an easier way to screen for Barrett's esophagus, a condition that can lead to esophageal cancer. The goal is to see if this non-invasive test, which collects cells from the esophagus, can accurately id…

This study is testing a new, simpler way to find Barrett's esophagus, a condition that can lead to a deadly type of esophageal cancer. Researchers want to see if a swallowable balloon device (EsoCheck) and a lab test (EsoGuard) can effectively screen people over 50 who are at ris…

This study is testing a new, less invasive way to check for Barrett's Esophagus, a condition that can increase the risk of esophageal cancer. Participants swallow a small capsule that releases a sponge to collect cells from the esophagus, which is then pulled back up by a string.…

This study is testing whether chemical markers found in a person's breath and blood can be used to detect early-stage stomach and esophageal cancer. Researchers will compare samples from 1,000 people, including those with cancer, those with a pre-cancerous condition called Barret…

This study is testing a new, swallowable capsule device designed to improve screening for Barrett's Esophagus, a condition that can lead to esophageal cancer. The capsule takes detailed pictures inside the esophagus and can collect tiny, targeted tissue samples for genetic analys…

This study is testing if a drug called obeticholic acid can prevent Barrett's esophagus from turning into cancer. It will involve 30 adults with Barrett's esophagus who will take either the drug or a placebo pill daily for six months. The main goal is to see if the drug reduces c…

This study is checking if it's safe for people with a low-risk form of Barrett's esophagus to stop having regular camera checks of their food pipe (endoscopies). It will follow over 3,100 patients in the Netherlands for at least 10 years to see how many develop serious cancer. Th…

This study is collecting data over 5 years to compare two methods doctors use to take small tissue samples from the esophagus during routine endoscopy procedures. Researchers want to see which method better helps predict which patients with heartburn might develop Barrett's esoph…

This study aims to find out how common Barrett's esophagus is in people with eating disorders who frequently make themselves vomit or regurgitate food. Researchers will use a simple, non-invasive test on 25 adults who have been purging for at least five years. The goal is to gath…

This study aims to collect real-world data on how well a newer, more precise technique works for removing precancerous growths in the esophagus and colon. It will follow 1,000 U.S. patients who are already scheduled to receive this procedure as part of their standard care. The go…

This study aims to understand how the esophagus changes during treatment for Barrett's esophagus, a condition that can lead to cancer. Researchers will measure stiffness and lining health in 10 patients receiving standard radiofrequency ablation therapy. The goal is to gather inf…