BARRETT ESOPHAGUS

This study is testing a simple, non-invasive method to detect early signs of Barrett's esophagus, esophageal cancer, and stomach cancer. Participants swallow a capsule attached to a string that collects cells from the esophagus and stomach. Researchers then analyze the DNA in tho…

This study tests a new, less invasive way to screen for Barrett's esophagus, a condition that can lead to esophageal cancer. Instead of using a long tube with a camera (endoscopy), participants swallow a small sponge on a string that collects cells from the esophagus. The collect…

This study tests a simple sponge-on-a-string device that people swallow to collect cells from the esophagus. The goal is to see if this non-invasive test can accurately detect Barrett's esophagus and early signs of esophageal cancer in people aged 50-85 with risk factors like chr…

This study tests a new way to detect Barrett's esophagus, a condition that can lead to cancer, without using a traditional endoscopy. Participants swallow a capsule with a sponge that collects cells from the esophagus. The cells are then tested for specific markers and compared t…

This study aims to see if a new office-based test can detect Barrett's esophagus—a condition that can lead to esophageal cancer—in people who do not have chronic heartburn. About 800 adults will answer a questionnaire, swallow a capsule balloon to collect cells, and have a lab te…

This study aims to see if certain chemicals in a person's breath and blood can help detect early-stage gastro-esophageal cancer. Researchers will compare samples from people with cancer, those with Barrett's esophagus (a pre-cancer condition), and healthy volunteers. Participants…

This study tests whether obeticholic acid can prevent cancer in people with Barrett's esophagus, a condition that raises the risk of esophageal cancer. The drug works by reducing damage from bile acids that flow back into the esophagus. About 30 adults with Barrett's esophagus wi…

This study follows over 3,000 people with low-risk Barrett's esophagus (a condition that can lead to esophageal cancer) who have stopped having routine endoscopic surveillance. Researchers want to see if stopping these scopes leads to a rise in advanced esophageal cancer over 10 …

This study watches how the esophagus changes in people getting radiofrequency ablation for Barrett's esophagus with abnormal cells. About 10 adults will have extra measurements during their routine endoscopies. The goal is to gather information that could help doctors predict tre…

This study is tracking how well a procedure called endoscopic submucosal dissection (ESD) works for removing abnormal growths in the esophagus and other parts of the digestive tract. Researchers will follow 1,000 adults who are already scheduled for this procedure as part of thei…

This study tests a new swallowable capsule that takes detailed images of the esophagus and collects tiny tissue samples from areas that look abnormal. The goal is to see if this method can safely gather enough tissue for genetic analysis to better predict cancer risk in people wi…

This study looks for Barrett's esophagus, a condition that can lead to cancer, in 25 adults with eating disorders who have been purging (vomiting or ruminating) for at least 5 years. Researchers will use a simple, non-endoscopic test to see how common Barrett's is in this group. …

This study looks at whether taking multiple saliva samples over time can better detect Barrett's esophagus, a condition that raises the risk of esophageal cancer. Researchers will collect saliva from 275 adults who have had or are scheduled for an upper endoscopy. The goal is to …

This study looks at two common ways to manage Barrett's esophagus with low-grade dysplasia—a condition where the lining of the esophagus has abnormal cells that rarely turn into cancer. One approach is regular check-ups with a camera and small tissue samples (surveillance). The o…

This study will collect data from 90,000 adults to compare two methods of taking tissue samples from the esophagus: standard forceps biopsies and a brush-based method called WATS3D. The goal is to see which approach better detects Barrett's esophagus, dysplasia, and other esophag…