Barrett esophagus
Clinical trials for Barrett esophagus explained in plain language.
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Barrett's esophagus treatment showdown: which procedure hurts less?
Disease control CompletedThis study compared two endoscopic treatments for Barrett's esophagus, a condition that can lead to esophageal cancer. The goal was to see which procedure—radiofrequency ablation or hybrid argon plasma coagulation—causes less pain and is safer from the patient's viewpoint. Sixty-…
Matched conditions: BARRETT ESOPHAGUS
Sponsor: Centre of Postgraduate Medical Education • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC
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Vinegar test spots hidden cancer in real time
Diagnosis CompletedThis study tested a new way to spot cancer in people with Barrett's esophagus, a condition that can lead to esophageal cancer. Doctors sprayed a weak vinegar solution on the esophagus and timed how long the tissue stayed white. They found that cancerous or pre-cancerous areas los…
Matched conditions: BARRETT ESOPHAGUS
Sponsor: Portsmouth Hospitals NHS Trust • Aim: Diagnosis
Last updated Jun 27, 2026 08:06 UTC
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New scope technique could catch esophagus cancer earlier
Diagnosis CompletedThis study tested whether a special camera technique (virtual chromoendoscopy) can find pre-cancerous or cancerous spots in Barrett's esophagus better than the standard method of taking random biopsies. 110 adults with Barrett's esophagus took part. The goal was to see if the new…
Matched conditions: BARRETT ESOPHAGUS
Sponsor: Nantes University Hospital • Aim: Diagnosis
Last updated Jun 27, 2026 07:57 UTC
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What do patients really want when facing oesophageal cancer surgery?
Knowledge-focused CompletedResearchers want to understand what patients with early oesophageal cancer value most when deciding whether to have major surgery. The study uses interviews and a choice experiment with about 118 people under care for Barrett's, dysplasia, or oesophageal cancer. Participants answ…
Matched conditions: BARRETT ESOPHAGUS
Sponsor: Portsmouth Hospitals NHS Trust • Aim: Knowledge-focused
Last updated Sep 20, 2026 00:00 UTC
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Can constipation drugs reveal hidden signals in gut tissue?
Knowledge-focused CompletedThis early study looked at how two approved constipation drugs, plecanatide and linaclotide, affect a chemical called cGMP in the small intestine. Researchers compared tissue samples from 43 adults with Barrett esophagus or GERD who took either drug or no drug. The goal was to me…
Matched conditions: BARRETT ESOPHAGUS
Phase 1 • Sponsor: University of Wisconsin, Madison • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
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Could a simple test replace the scope for Barrett's esophagus screening?
Knowledge-focused CompletedThis study looked at whether a non-endoscopic device (EsoCheck) and a biomarker test (EsoGuard) can help doctors decide when to refer patients for a standard upper endoscopy to screen for Barrett's esophagus. 97 doctors reviewed patient cases and made referral decisions, first wi…
Matched conditions: BARRETT ESOPHAGUS
Sponsor: Lucid Diagnostics, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC