Vinegar test spots hidden cancer in real time
NCT ID NCT01618643
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a new way to spot cancer in people with Barrett's esophagus, a condition that can lead to esophageal cancer. Doctors sprayed a weak vinegar solution on the esophagus and timed how long the tissue stayed white. They found that cancerous or pre-cancerous areas lost the white color at a different rate than healthy tissue. The goal was to make it easier to tell which spots need treatment, without taking extra biopsies.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
-
197 people
The number who actually took part.
- Started
-
Nov 2010
- Finished
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Sep 2012
- Lead sponsor
-
A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients undergoing surveillance for Barrett's oesophagus
- Ages
-
18 years and older
- Sex
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Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients with known Barrett's metaplasia under surveillance * Patients with Barrett's metaplasia who had undergone endoscopic treatment for neoplasia previously and were under surveillance for metachronous neoplasia * Patients suspected of neoplasia referred for endoscopic mucosal resection or other targeted endoscopic treatment of the lesion Exclusion Criteria: * Oesophagitis * Contact bleeding * Acute mucosal trauma
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Portsmouth Hospitals NHS trust
Portsmouth, Hampshire, PO76TS, United Kingdom
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a Pre-Surgery checklist predict who will still have reflux after fundoplication?
- New acid blocker may offer stronger reflux control for Barrett's esophagus
- Can we spot cancer before it starts? a massive study aims to find out
- Which biopsy method best spots early esophageal cancer?
- New cutting tool may outperform heat therapy for Barrett's esophagus