Nantes University Hospital

This study is testing whether a fecal microbiota transplant (FMT) can delay or prevent the return of pouchitis, a painful gut inflammation, in people who have had surgery for ulcerative colitis. It compares the real FMT treatment against a sham (fake) transplant in 42 participant…

This study is testing a two-part strategy for adults newly diagnosed with multiple myeloma. After initial treatment, patients receive different drug combinations based on whether tiny amounts of cancer cells are still detectable. The goal is to see if these combinations can elimi…

This study is testing whether people with well-controlled eczema can safely take their medication (dupilumab) less often. It will compare a reduced dosing schedule to the standard schedule in 256 teens and adults over one year. The goal is to see if spacing out injections can mai…

This study is comparing two ways to fix a severe leak in the heart's mitral valve. It is testing a less invasive procedure using a small clip (MitraClip) against traditional open-heart surgery. The goal is to see if the clip procedure works as well as surgery for high-risk patien…

This study is testing if giving patients extra oxygen through a nasal tube after ankle fracture surgery helps prevent complications like poor wound healing and infections. It involves 200 patients who are at higher risk for these problems. Half will receive the oxygen therapy dur…

This study is testing whether a highly concentrated extract from blue-green algae (spirulina), called Phycocare®, can protect against nerve damage caused by a chemotherapy drug called oxaliplatin. The trial involves 110 adults with advanced stomach, intestinal, or pancreatic canc…

This study aims to discover the genetic causes of two rare, complex heart defects present at birth. Researchers will analyze DNA from about 600 children with these conditions and their parents to find new genetic links. The goal is to build knowledge that could lead to better, mo…