WEIGHT LOSS

This study tested a 24-week virtual program that combined prescription weight-loss medications (like Wegovy and Zepbound) with behavioral coaching from WeightWatchers. Researchers wanted to see if this combined approach helped people lose more weight than medication alone might. …

This study looked at how a diabetes prevention lifestyle program affects weight, heart health, and stress levels in adults from socioeconomically disadvantaged backgrounds. Researchers followed 15 participants for 18 months to see if the program helped them maintain weight loss a…

This study aimed to find out which of two surgeries works better for people with Superior Mesenteric Artery Syndrome (SMAS), a rare condition where a major blood vessel pinches part of the small intestine, causing severe nausea, vomiting, and weight loss. Twenty participants with…

This study tested whether an immersive virtual reality (VR) diet education program could help people with fatty liver disease manage their condition. Twenty participants tried the VR program, which teaches about food portions and preparation, alongside video counseling, and were …

This study tested whether giving people personalized lifestyle advice based on their DNA test results would help them lose more weight than receiving general healthy living guidance. It involved 53 overweight or obese Korean adults who were interested in managing their weight. Pa…

This study tested a weight loss program designed specifically for adults with long-term spinal cord injuries. The program combined three approaches: portion-controlled meals, self-monitoring tools, and lifestyle coaching. Researchers aimed to find the best combination to help peo…

This study tested a new daily oral medication, VK2735, to help with weight management. It involved 280 adults who were obese or overweight with at least one related health condition, like high blood pressure. Participants took either the drug or a placebo pill for 13 weeks to see…

This study tested whether training regular healthcare staff, like nurses and medical assistants, to provide lifestyle coaching could help people maintain weight loss over two years. It involved 269 adults who had recently lost weight and compared those who received coaching throu…

This study looked at whether starting a weight loss medication called liraglutide helps people who are still obese six months after weight loss surgery. Researchers observed 100 patients to see if taking the drug early leads to better weight loss and improved health markers like …

This study looked at whether weight-loss surgery (vertical sleeve gastrectomy) could improve the health of the pancreas, kidneys, and heart in teens and young adults with type 2 diabetes. Researchers enrolled 24 young people, aged 12-21, who were scheduled for this surgery. They …

This study tested whether losing weight before starting IVF treatment helps overweight women have a baby. Researchers split 158 women into two groups: one followed a 3-month diet and exercise plan before IVF, while the other received standard care. The goal was to see if the weig…

This small, completed pilot study tested whether following a low-carbohydrate, higher-protein diet could help people lose more weight while they were already taking the injectable weight-loss medication semaglutide. For 12 weeks, 60 participants were randomly assigned to follow e…

This study tested whether an online family support program could work well alongside a standard weight loss program for Black adults. Researchers wanted to see if adding family skills training online would be practical and acceptable to participants. The program focused on improv…

This study tested an online program called Sleep GOALS, designed to help new mothers lose weight after giving birth. The program focused on improving sleep, diet, and physical activity habits. Researchers enrolled 40 postpartum women to see if the program was easy to use, accepta…

This study tested whether using existing social networks could help people in Hispanic and Somali immigrant communities lose weight and improve their heart health. Researchers worked with 475 participants in Minnesota to see if group support within their communities led to better…

This study compared two popular diet approaches for managing obesity: intermittent fasting and the Mediterranean diet. Researchers followed 120 obese adults for 4 weeks, with half following a time-restricted eating schedule and half following a structured Mediterranean meal plan.…

This study tested whether a smartphone app could help people with severe obesity lose weight before having gastric bypass surgery. Researchers compared the app, which provided support and tracking, to the standard preoperative education and meetings. The goal was to see if using …

This study tested a new digital care approach for families with children living with obesity in Sweden. It compared standard in-person clinic visits to a program that replaced half the visits with a smartphone app for tracking health goals and communicating with caregivers. The g…

This study tested whether adding specific mindfulness and acceptance skills to standard remote weight loss counseling helps people lose more weight. Researchers worked with 276 adults who were overweight or obese to see if learning awareness, acceptance, and values-clarity techni…

This study tested if a weight loss drug (Semaglutide) combined with a very low-calorie diet could better treat a serious brain pressure condition called Idiopathic Intracranial Hypertension (IIH). It involved 38 women with new IIH and obesity, comparing the drug and diet plan to …

This study tested a new 2-year weight loss program called 'Med-South,' which adapts a Mediterranean-style diet for Southern U.S. preferences. Researchers compared it directly to the popular WW (Weight Watchers) program. The goal was to see which approach helped 360 adults with ob…

This study tested if group doctor visits, combined with cooking classes and free healthy groceries, are a helpful way to manage weight. 43 adults with obesity from a Duke weight management clinic were randomly assigned to either attend these group sessions or use online modules. …

This study tested three different approaches to help older adults with type 2 diabetes improve their health: a specific exercise routine, a plant-based Mediterranean diet, and a diabetes medication. One hundred inactive participants aged 65 and over were assigned to one of these …

This study tested a year-long health coaching program designed to help overweight or obese youth who are also receiving mental health treatment. The program involved a health coach who worked with both the young person and their parent to promote healthy eating and physical activ…

This study tested a program to help South Asian adults with pre-diabetes lose weight and prevent type 2 diabetes. Nearly 1,000 participants worked with community health coaches and their doctors used special electronic health record alerts. The main goal was to see if this linked…

This study tested whether mindfulness training could help adults who had recently lost weight keep it off. Researchers worked with 48 people, including some who had bariatric surgery, to see if learning mindful awareness of eating behaviors would prevent weight regain over 6 mont…

This study tested whether fasting for 14 hours overnight could help prevent blood cancer in overweight people with early-stage blood cell conditions. 23 participants were randomly assigned to either follow the fasting schedule or receive general healthy lifestyle advice for 4 mon…

This study tested whether a fully automated smartphone app could be as effective as a traditional human coach program at helping people with prediabetes lower their risk of developing type 2 diabetes. 368 adults were randomly assigned to use either the app with a smart scale or a…

This study tested whether adding the anti-nausea medication ondansetron (Zofran) to standard bowel prep helps children complete their colonoscopy preparation more comfortably and effectively. Researchers compared children using just laxatives to those using laxatives plus ondanse…

This study aimed to see if eating snack bars with added fiber could help reduce common stomach side effects, like nausea and bloating, in people taking GLP-1 weight loss medications. Fifty adults already using these medications tried different snack bars for one week each and rep…

This study aimed to understand why people have trouble sticking to diet and exercise plans during weight loss programs. Researchers used smartphone surveys and fitness trackers to monitor 119 adults with obesity in real-time as they tried to lose weight. The goal was to identify …

This study aimed to understand why some people gain or lose weight more easily than others. Researchers measured how participants' bodies burned calories during periods of overeating and fasting to see if this could predict their weight change. The goal was to gather knowledge th…

This study aimed to understand how weight loss affects muscle energy production in women with ovarian or endometrial cancer. Researchers compared 70 women with cancer-related weight loss to women having surgery for non-cancerous conditions. They analyzed muscle and tissue samples…

This study aimed to create a tool that predicts which families are likely to drop out of pediatric weight management programs early. Researchers followed over 1,200 children and a parent from four different programs for six months, collecting data on family life, health, and stre…