Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Can exercise, diet, or a pill help older diabetics stay strong?

NCT ID NCT03560375

Disease control Sponsor: Tel-Aviv Sourasky Medical Center Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This completed study looked at three ways to help people aged 65 and older with type 2 diabetes improve their physical and metabolic health. One group did home-based circuit resistance training, another followed a plant-based Mediterranean diet, and the third took the diabetes drug empagliflozin. After 10 weeks, the diet and drug groups also started exercising. The goal was to see if these approaches could improve body composition, muscle strength, and blood sugar control.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
empagliflozin
What this could lead to
If successful, this could show that simple lifestyle changes or a common diabetes drug help older adults with diabetes maintain muscle strength and control blood sugar.
What could go wrong
This is a small, completed trial with 100 participants, so results may not apply to everyone. The interventions are short-term (10-20 weeks), so long-term benefits or risks are unknown.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

100 people

The number who actually took part.

Started

May 2018

Finished

Feb 2021

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

65 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Subjects who have type 2 diabetes mellitus in accordance with American Diabetes Association guidelines and: 1. Are ≥65 years of age (inclusive) on the day of signing the informed consent form. 2. Perform \<2 days a week of any leisure aerobic physical activity (PA), who are able to walk independently either with or without an assistance device (cane or walker). 3. HbA1C ≥6.5% to ≤8%. Exclusion Criteria: 1. Recent use of steroid agents (\<6 months, replacement therapy is allowed) 2. Uncorrected hypothyroidism \[thyroid stimulating hormone (TSH) \> 6 mlU/L\] 3. Diagnosis of malignancy within the past 5 years except for non-melanoma skin cancer. 4. Severe kidney disease (eGFR\<45cc/ml) 5. Active depression 6. Recent (≤6 months) or unstable cardiovascular condition; New York Heart Association (NYHA) Class 3 or higher congestive heart failure; 7. Subjects with PA limiting pain due to neuropathy 8. Subjects who are in an active nutritional therapy changed their diet recently (\<1 month) and/or in a weight-loss program (actively losing weight). 9. Has other severe acute or chronic medical or psychiatric condition or laboratory abnormality that may increase the risk associated with study participation or may interfere with the interpretation of study results.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Diabetes mellitus type 2 are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

Sarcopenia type 2 diabetes mellitus Weight Loss

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Diabetes mellitus type 2 Sarcopenia Weight loss

Contacts and locations

Locations

  • The Institute of Endocrinology Metabolism and Hypertension

    Tel Aviv, 64239, Israel

More trials for these conditions

Other studies related to the condition(s) this trial covers.