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Heart failure study reveals hidden danger of unintentional weight loss

NCT ID NCT06259045

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at how common cardiac cachexia (unintentional weight loss) is in people with advanced heart failure and how it affects their outcomes. Researchers followed about 200 patients for one year to compare survival and hospitalizations between those with and without the condition. The goal was to better understand the impact of cachexia and encourage future research on treatments.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

261 people

The number who actually took part.

Started

Feb 2024

Finished

Apr 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients with advanced heart failure are being recruited in to this study

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Meets one of the "I NEED HELP" markers for advanced heart failure * Has capacity to consent and participate in the study * Age 18 years and older Exclusion Criteria: * Does not have at least one "I NEED HELP" marker for advanced heart failure * Does not consent to or has not got the ability to participate in the study * Is below the age of 18 years

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Conditions

The condition(s) this trial relates to.

advanced heart failure Cachexia Frailty heart failure Weight Loss

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Harefield Hospital

    London, London, UB96JH, United Kingdom

More trials for these conditions

Other studies related to the condition(s) this trial covers.