Can cutting carbs boost semaglutide weight loss?
NCT ID NCT07280403
First seen Jan 11, 2026 · Last updated Jun 20, 2026 · Updated 24 times
Summary
This completed pilot trial tested whether adding a low-carb, high-protein diet (like Atkins) helps people lose more weight while taking the injectable drug semaglutide. 60 overweight or obese adults were randomly assigned to follow either a low-carb or low-fat diet for 3 months. Researchers tracked weight, blood sugar, and body composition changes.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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INQUIS Clinical Research
Toronto, Ontario, M5C2N8, Canada
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
low-carbohydrate diet
What this could lead to
If it works, this could show that adding a low-carb diet to semaglutide helps people lose more weight than a low-fat diet.
What could go wrong
This is a small pilot trial with only 60 people over 3 months, so results may not apply to everyone. The diet is hard to stick with long-term.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.