Can cutting carbs boost semaglutide weight loss?

NCT ID NCT07280403

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This completed pilot trial tested whether adding a low-carb, high-protein diet (like Atkins) helps people lose more weight while taking the injectable drug semaglutide. 60 overweight or obese adults were randomly assigned to follow either a low-carb or low-fat diet for 3 months. Researchers tracked weight, blood sugar, and body composition changes.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
low-carbohydrate diet
What this could lead to
If it works, this could show that adding a low-carb diet to semaglutide helps people lose more weight than a low-fat diet.
What could go wrong
This is a small pilot trial with only 60 people over 3 months, so results may not apply to everyone. The diet is hard to stick with long-term.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

obesity disorder Weight Loss

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • INQUIS Clinical Research

    Toronto, Ontario, M5C2N8, Canada

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