WEIGHT LOSS

This study is testing a new smartphone app designed to help people manage their weight. The app uses AI and cognitive behavioral therapy (CBT) techniques to track food and mood, aiming to reduce cravings and promote a healthier lifestyle. Researchers will follow 100 adults with o…

This study is testing whether VK2735 injections help people lose weight and keep it off. It involves 4,500 adults who are obese or overweight with related health conditions like high blood pressure or sleep apnea. Participants receive either the actual drug or a placebo injection…

This study is testing whether a weight loss program designed like a video game can help men lose weight and keep it off. 228 overweight or obese men will use a mobile app for 12 months; some will get a standard version, while others get a gamified version with team competitions a…

This study is testing whether a weight management program offered through schools and hospitals can help children and teenagers with obesity lose weight and adopt healthier lifestyles. It involves 700 young people in Denmark, aged 2 to 18, who are above a healthy weight. The main…

This study is testing whether two specific probiotic supplements, TCI378 and TCI507, can help adults lose weight and improve health markers like cholesterol. About 96 overweight adults will take the supplements daily for two months. Researchers will measure changes in body fat, w…

This study aims to see if combining time-restricted eating (limiting daily food intake to a specific window) with high-intensity interval training (short bursts of intense exercise) can improve health in people with metabolic syndrome. Researchers will compare these approaches in…

This study is testing whether a comprehensive digital weight loss program, delivered through a patient's online health portal, helps people lose more weight than receiving basic health education. About 250 overweight or obese adults from diverse backgrounds will be randomly assig…

This study is testing a new approach to help rural families manage weight. It compares two versions of a televideo program: one where parents get coaching first, then join sessions with their child, versus a program where parents and children attend together from the start. The g…

This study aimed to see if helping parents with their nutrition and weight could also help prevent obesity in their young children. Parents would have joined a free online nutrition program and some might have received weight loss medication. Researchers planned to measure change…

This study is testing whether the antidepressant mirtazapine can improve poor appetite and weight loss in people with advanced cancer. About 98 participants were randomly assigned to receive either the drug or a placebo pill for two weeks, followed by the drug for everyone. Resea…

This study is testing whether a drug called anamorelin, combined with a home exercise program and nutritional counseling, can help reduce severe fatigue in people with advanced, incurable solid tumors. Participants take the drug daily for 6 weeks while following the exercise and …

This study aims to understand why some people's bodies slow down their metabolism more than others after losing weight. Researchers will follow 60 adults with obesity as they lose weight, measuring their metabolism and various hormones in their blood and urine over 18 months. The…

This study aims to find out if people taking GLP-1 weight loss medications (like Ozempic or Wegovy) need to take multivitamins to prevent nutrient deficiencies. Researchers will compare vitamin and mineral levels in 246 adults who either take a multivitamin or a placebo pill for …

This study aims to understand what factors help people with obesity succeed at losing weight. Researchers will follow 500 adults from a weight loss clinic, collecting detailed health and lifestyle information. The goal is to use this data to build better, more personalized weight…

This study aims to understand how the liver's energy production changes in people with fatty liver disease (NASH) who are undergoing weight loss surgery. Researchers will measure how the liver burns fat and makes sugar in 30 participants before their surgery. The goal is to see i…

This study aims to collect long-term data on 5,000 patients who have had endoscopic or surgical weight loss procedures. Researchers will track weight changes, health improvements, side effects, and costs over 10 years to better understand which treatments work best. The goal is t…