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Multivitamins may protect against nutrient loss in GLP-1 users

NCT ID NCT07234916

First seen Nov 19, 2025

Summary

This study looks at whether taking a daily multivitamin can prevent vitamin and mineral deficiencies in people using GLP-1 drugs (like tirzepatide) for weight loss. About 246 adults with obesity who have been on a stable GLP-1 dose for at least 3 months will be randomly assigned to receive either a multivitamin or a placebo for 12 months. Researchers will measure key nutrients like vitamin B12, vitamin D, and iron in the blood to see if supplementation makes a difference.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Erasmus MC

    Rotterdam, Netherlands

  • WeightWorks Clinics

    Amersfoort, Netherlands

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

multivitamin supplement

What this could lead to

If it works, this could show that taking a daily multivitamin helps prevent nutrient deficiencies in people using GLP-1 weight-loss drugs.

What could go wrong

This is a small, early-stage trial focused on blood levels, not on preventing actual health problems. The results may not apply to everyone, and multivitamins might not make a meaningful difference.

Conditions

The condition(s) this trial relates to.

Malnutrition nutritional deficiency disease Obesity obesity disorder Weight Loss

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.