GLP-1

This study aims to find the best weight-loss medication for people with bipolar disorder by matching drugs to specific obesity types (like 'hungry brain' or 'hungry gut'). About 100 adults aged 18-65 with bipolar or schizoaffective disorder and obesity will receive one of three F…

This study looks at whether adding a GLP-1 appetite suppressant to behavioral therapy helps people with severe obesity and binge eating disorder more than therapy alone. About 80 adults will be split into two groups: one gets the drug plus therapy, the other gets therapy only. Re…

This study looks at how GLP-1 and GIP/GLP-1 medications affect what people eat, their weight, and overall health. Researchers will follow 100 adults with overweight or obesity for one year, tracking changes in diet, body composition, and metabolism. The goal is to understand both…

This study looks at bone health in teens aged 12-21 with obesity who take GLP-1 weight-loss drugs compared to those using only lifestyle changes. Over 24 months, participants will have check-ups, lab tests, and bone scans. The goal is to see if these drugs affect bone strength, h…

This study looks at how tirzepatide, a weight-loss drug, affects muscle mass and strength in adults aged 50 and older with obesity. Researchers want to know if losing weight with this drug also leads to muscle loss, which could cause weakness or frailty. About 20 participants wil…

This study looks at whether a special supplement can help fill nutrient gaps and improve gut health in adults taking GLP-1 medications like Ozempic or Wegovy. Researchers will compare the supplement to a placebo in 120 people aged 18-59. The goal is to see if the supplement impro…

This study looks at how estrogen levels influence changes in body composition, muscle function, and bone health in women aged 35-60 who are starting a GLP-1RA medication for weight loss. Researchers will measure weight, lean and fat mass, bone density, and muscle strength over ti…

This study looks at how different amounts of a slowly digestible starch affect a hormone called GLP-1, which helps control appetite. Healthy adults will drink test beverages and have their blood drawn to measure GLP-1, insulin, and blood sugar levels. They will also rate their fu…

This study looks at how GLP-1 and GIP agonists (medicines for diabetes and weight loss) affect bowel preparation quality in people getting a colonoscopy. Researchers will compare what happens when patients either skip or take their usual dose before the procedure. The goal is to …

This study tracks muscle and fat changes in 50 adults starting semaglutide for type 2 diabetes or weight loss. Over 12 months, participants undergo MRI scans, physical tests, and blood draws. The goal is to understand how the drug affects muscle health, especially in people at ri…