GLP-1

This study tests whether matching specific weight-loss medications (Wegovy, Contrave, or Qsymia) to a person's obesity type (e.g., 'hungry brain' or 'emotional hunger') helps people with bipolar disorder lose weight safely. One hundred adults with bipolar or schizoaffective disor…

This study tests whether a nutritional supplement called AG1 can help fill nutrient gaps and improve gut health in 120 adults taking GLP-1 medications like Ozempic or Wegovy. Participants will take either the supplement or a placebo for a period, and researchers will measure chan…

This study looks at how popular weight-loss medications (GLP-1 and GIP/GLP-1 analogs) affect what people eat, their metabolism, and behavior over a year. Researchers will track 100 adults with overweight or obesity to see changes in weight, body composition, and diet quality. The…

This study looks at whether adding GLP-1 weight-loss drugs to cognitive behavioral therapy helps adults with severe obesity and binge eating disorder. About 80 participants will either take a GLP-1 drug or not, while both groups attend therapy sessions. Researchers will track cha…

This study is looking at whether GLP-1 receptor agonists—drugs used for type 2 diabetes and obesity—can also improve dry eye disease. Researchers will measure changes in tear stability and eye surface health in 100 patients who have not taken these drugs before. The goal is to un…

This study looks at how slowly digestible carbohydrates (a type of starch) affect a hormone called GLP-1, which helps control appetite. Researchers will give healthy adults different amounts of raw corn starch and measure their GLP-1 levels, blood sugar, and feelings of fullness …

This study uses advanced MRI scans to track changes in muscle and fat in the body and heart over 12 months in 50 adults starting semaglutide for type 2 diabetes or weight loss. Participants will undergo MRI scans, physical tests, blood samples, and questionnaires. The goal is to …

This study tracks bone health in 120 teens aged 12–21 with obesity who are either starting a GLP-1 drug (like semaglutide) or following lifestyle changes. Over 24 months, researchers measure bone density and strength using scans and lab tests. The goal is to see if these popular …

This study looks at how tirzepatide, a weight-loss drug, affects muscle mass and strength in adults aged 50 and older with obesity. Researchers want to know if losing weight with this drug also causes harmful muscle loss that could lead to frailty. Twenty participants will take t…

This study looks at how estrogen levels influence body composition and muscle function in midlife women (ages 35-60) who are starting a GLP-1RA medication for weight loss. Researchers will measure changes in weight, muscle mass, bone density, and strength over time. The goal is t…

This study looks at how GLP-1 and GIP agonists (medications used for diabetes and weight loss) affect bowel preparation quality in adults scheduled for a colonoscopy. Researchers want to see if these drugs increase the chance of poor bowel prep, and whether pausing the medication…