GLP-1
Clinical trials for GLP-1 explained in plain language.
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Can a diabetes drug improve joint replacement outcomes?
Disease control Not yet recruitingThis trial tests whether taking a GLP-1 medication (semaglutide) for at least six months before hip or knee replacement surgery can improve recovery and reduce complications in patients with obesity. Participants will be randomly assigned to receive either the medication plus beh…
Matched conditions: GLP-1
Phase: PHASE4 • Sponsor: Nova Scotia Health Authority • Aim: Disease control
Last updated Aug 12, 2026 00:00 UTC
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New study tests lifestyle program to keep weight off after stopping popular obesity drugs
Disease control Not yet recruitingThis pilot study tests whether a 10-week behavioral program can help people maintain weight loss after stopping GLP-1 or other anti-obesity medications. The program includes medically tailored meals, a YMCA membership, and a meditation component. Researchers will follow 64 partic…
Matched conditions: GLP-1
Phase: NA • Sponsor: University of Alabama at Birmingham • Aim: Disease control
Last updated Jun 28, 2026 00:00 UTC
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New study tests if exercise can save your muscles while on Weight-Loss drugs
Disease control Not yet recruitingThis study tests whether a 12-week program of exercise and personalized diet counseling can help preserve muscle mass in obese adults taking GLP-1 medications like Wegovy. Twenty participants aged 40-55 will be followed to see if these lifestyle changes prevent the muscle loss of…
Matched conditions: GLP-1
Phase: PHASE4 • Sponsor: William Marsh Rice University • Aim: Disease control
Last updated Jun 27, 2026 12:25 UTC
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Could a diabetes drug boost rectal cancer treatment?
Disease control Not yet recruitingThis study tests whether adding a weight-loss medication (a GLP-1 drug) to standard chemo-radiation before surgery helps rectal cancer patients with a high BMI. About 42 participants will either get the drug plus standard treatment or standard treatment alone. Researchers will me…
Matched conditions: GLP-1
Phase: PHASE2 • Sponsor: St. James's Hospital, Ireland • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC
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Probiotic pill tested to stop weight regain after GLP-1s
Disease control Not yet recruitingThis study tests whether a daily probiotic supplement (UltraFlora Triplebiotic) can help adults avoid regaining weight after they stop taking GLP-1 medications like Ozempic or Wegovy. About 128 people who recently stopped GLP-1 treatment will take the supplement or a placebo for …
Matched conditions: GLP-1
Phase: NA • Sponsor: Metagenics, Inc. • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC
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Could a Weight-Loss drug change how your body handles alcohol?
Knowledge-focused Not yet recruitingThis study investigates whether tirzepatide, a medication used for weight loss, alters the way the body processes alcohol. Five adults aged 21-55 who take tirzepatide will consume a standard amount of alcohol, and researchers will measure blood alcohol levels, elimination rates, …
Matched conditions: GLP-1
Phase: PHASE1 • Sponsor: University of Wisconsin, Madison • Aim: Knowledge-focused
Last updated Aug 13, 2026 00:00 UTC
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Can a protein drink help GLP-1 users keep muscle and avoid weight regain?
Knowledge-focused Not yet recruitingThis study tests whether special amino acid-enriched drinks can help people on GLP-1 weight-loss drugs maintain muscle and prevent weight regain. Eight adults aged 30-65 who recently started GLP-1 medication will drink different supplement beverages, and researchers will measure …
Matched conditions: GLP-1
Phase: NA • Sponsor: Nutraceutical Innovations LLC • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC
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Do GLP-1 drugs shield you from tempting food ads? new study investigates
Knowledge-focused Not yet recruitingThis study looks at whether GLP-1 weight-loss medications reduce cravings and unhealthy food choices triggered by food advertisements. Fifty adults taking tirzepatide will view food or tech ads and report their cravings and food intake. The goal is to understand if these drugs ma…
Matched conditions: GLP-1
Phase: NA • Sponsor: Penn State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC