GLP-1
Clinical trials for GLP-1 explained in plain language.
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Could a diabetes drug boost rectal cancer treatment?
Disease control Not yet recruitingThis study tests whether adding a GLP-1 weight-loss drug (like semaglutide) to standard chemo-radiation before surgery helps rectal cancer patients with a high BMI. Researchers will measure weight loss, tumor response, and survival in 42 participants. The goal is to see if the dr…
Matched conditions: GLP-1
Phase: PHASE2 • Sponsor: St. James's Hospital, Ireland • Aim: Disease control
Last updated May 13, 2026 16:02 UTC
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New study aims to stop muscle loss during popular weight loss drug treatment
Disease control Not yet recruitingThis study looks at whether a 12-week program of exercise and personalized diet advice can help prevent muscle loss in obese adults who are taking GLP-1 medications (like semaglutide) for weight loss. The researchers will measure changes in muscle mass, strength, and fitness in 2…
Matched conditions: GLP-1
Phase: PHASE4 • Sponsor: William Marsh Rice University • Aim: Disease control
Last updated May 13, 2026 16:00 UTC
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Digital coaching aims to boost health in GLP-1 users
Disease control Not yet recruitingThis study will test whether the Noom digital lifestyle program helps adults who are taking GLP-1 medications (like Wegovy or Ozempic) improve their diet and physical activity. About 220 participants will use the program for 4 months while wearing a Fitbit to track activity. Rese…
Matched conditions: GLP-1
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Disease control
Last updated May 11, 2026 20:40 UTC
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New study tests if lifestyle changes can replace Weight-Loss drugs
Disease control Not yet recruitingThis study tests a 10-week behavioral program to help people maintain weight loss after stopping GLP-1 or other anti-obesity medications. 64 adults who lost at least 15% of their body weight on these drugs will be followed for 6 months. The program includes meal plans, gym member…
Matched conditions: GLP-1
Phase: NA • Sponsor: University of Alabama at Birmingham • Aim: Disease control
Last updated May 11, 2026 20:38 UTC
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New study tests probiotic to keep weight off after stopping GLP-1 drugs
Disease control Not yet recruitingThis study tests whether a probiotic supplement called UltraFlora Triplebiotic can help prevent weight regain in adults who have stopped taking GLP-1 weight-loss medications. About 128 adults who recently stopped GLP-1 treatment will take the supplement or a placebo for 3 months.…
Matched conditions: GLP-1
Phase: NA • Sponsor: Metagenics, Inc. • Aim: Disease control
Last updated May 04, 2026 16:23 UTC
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Can Weight-Loss drugs silence food cravings from ads?
Knowledge-focused Not yet recruitingThis study looks at whether GLP-1 medications (like tirzepatide) reduce how much food ads make you crave and eat. About 50 adults on these drugs will view food or non-food ads and report their cravings and food choices. The goal is to understand if these medications help people r…
Matched conditions: GLP-1
Phase: NA • Sponsor: Penn State University • Aim: Knowledge-focused
Last updated May 14, 2026 12:05 UTC