GLP-1

This study tests whether matching weight-loss medications to a person's specific obesity type (like 'hungry brain' or 'emotional hunger') helps people with bipolar disorder lose weight safely. About 100 adults aged 18-65 will take one of three FDA-approved drugs or join a weight-…

This study looks at how GLP-1 and GIP/GLP-1 medications affect what people eat, their metabolism, and behavior over a year. About 100 adults with overweight or obesity will be followed before starting treatment and at 3, 6, and 12 months. Researchers will measure weight loss, bod…

This study looks at whether adding a GLP-1 appetite suppressant to behavioral therapy helps people with severe obesity and binge eating disorder. About 80 adults will be split into two groups: one gets the drug plus therapy, the other gets therapy alone. Researchers will track ch…

This study looks at how slowly digestible carbohydrates (like raw corn starch) affect a hormone called GLP-1, which helps control appetite. Healthy adults aged 18-45 will drink different amounts of starch and have their blood tested over several hours. The goal is to find the bes…

This study looks at bone health in 120 teens and young adults (ages 12-21) with obesity over 2 years. Some take GLP-1 weight-loss drugs, others use lifestyle changes. Researchers measure bone density and strength to see if the drugs affect bones differently. Participants also tak…

This study looks at whether a special supplement can help people taking GLP-1 medications (like Ozempic or Wegovy) get the nutrients they might be missing and improve their gut health. Researchers will track 120 adults aged 18-59 who are on a steady dose of their GLP-1 drug. Part…

This study tracks muscle and fat changes in 50 adults starting semaglutide for type 2 diabetes or weight loss. Over 12 months, participants undergo MRI scans and physical tests to see how the drug affects muscle mass and function. The goal is to understand risks of muscle loss an…

This study looks at how estrogen levels influence changes in body composition, muscle function, and bone health in women aged 35-60 who are starting a GLP-1RA medication for weight loss. Researchers will measure weight, lean and fat mass, bone density, and muscle strength. The go…

This study looks at how tirzepatide, a weight-loss drug, affects muscle mass and strength in adults aged 50 and older with obesity. Researchers want to know if losing weight with this drug also causes harmful muscle loss that could lead to weakness or frailty. Twenty participants…

This study aims to understand if continuing GLP-1 or GIP agonist medications (used for diabetes and weight loss) affects how well patients prepare for a colonoscopy. Researchers will compare people who take their usual dose before the procedure to those who skip it, looking at bo…