Teens on GLP-1 drugs: are their bones at risk?

NCT ID NCT06903923

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tracks bone health in 120 teens aged 12–21 with obesity who are either starting a GLP-1 drug (like semaglutide) or following lifestyle changes. Over 24 months, researchers measure bone density and strength using scans and lab tests. The goal is to see if these popular weight-loss drugs affect growing bones.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

GLP-1 receptor agonist (e.g., liraglutide, semaglutide)

What this could lead to

If successful, this study could show whether GLP-1 drugs affect bone strength in teens, helping doctors make safer treatment choices.

What could go wrong

This is a small, early-phase observational study, not a large trial. Results may not apply to all teens, and bone changes may take longer to appear.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder Pediatric Obesity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Virginia Medical Center

    RECRUITING

    Charlottesville, Virginia, 22903, United States

    Contact Email: •••••@•••••

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••