Weight loss drug may weaken muscles in seniors, new study warns

NCT ID NCT06811324

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how tirzepatide, a weight-loss drug, affects muscle mass and strength in adults aged 50 and older with obesity. Researchers want to know if losing weight with this drug also causes harmful muscle loss that could lead to frailty. Twenty participants will take tirzepatide for 6 months and have their muscle, strength, and walking ability measured. The goal is to better understand the risks and benefits for older adults using this medication.

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder Sarcopenia Weight Loss

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Texas Health Science Center at San Antonio

    RECRUITING

    San Antonio, Texas, 78229, United States

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